摘要:
目的研究血浆内脂素浓度与成人单纯性肥胖及其代谢指标的相关性.方法对171例健康体检者分为肥胖组(BMI≥25 kg/m)2和非肥胖组(BMI<25 kg/m)2,分别测量身高、体重、腰围、臀围和血压,计算BMI和WHR;测定血清空腹葡萄糖(FPG)、空腹胰岛素(Fins)、总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-c)和高密度脂蛋白胆固醇(HDL-c)水平.采用酶免疫分析法测定空腹血浆内脂素水平,分析其与BMI、WHR和代谢指标间的相关性.结果 (1)肥胖组的BMI、WHR、FPG、Fins、UA均显著高于非肥胖组,HDL-c显著低于非肥胖组;(2)肥胖组空腹血浆内脂素浓度高于非肥胖组,差异无统计学意义(P>0.05);(3)肥胖组血浆内脂素水平与臀围、收缩压呈正相关.多元逐步回归分析结果表明,臀围是肥胖者血浆内脂素浓度的独立影响因素.结论肥胖者血浆内脂素浓度与非肥胖者无显著差异.臀围是肥胖者空腹血浆内脂素浓度的主要影响因素.
关键词:
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成人 /
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肥胖 /
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内脂素 /
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脂肪细胞因子
Abstract:
Objective To investigate the plasma concentration of visfatin in obesity patients and non-obesity controls and its correlation with the metabolic characteristics of obesity.Methods The height,body weight,waistline,and blood pressure of 171 healthy subjects were measured,and the BMI and WHR were calculated.The serum levels of FPG,Fins,TC,TG,LDL-c and HDL-c were also measured.The serum level of Visfatin was measured with ELISA assay,and its correlation with BMI,WHR and metabolic indexes was analyzed.Results(1...
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