尤瑞克林冶疗ACI的临床疗效及对血清CPR及IL-8的影响
Curative Effect of Urinary Kallidinogenase on Serum C-reactive Protein and IL-8 in Patients with Acute Cerebral Infarction
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摘要: 目的探讨尤瑞克林治疗急性脑梗死(AC)I的临床疗效及对血清C-反应蛋白(CRP)和白介素-8(IL-8)水平的影响.方法将66例急性脑梗死患者随机分为对照组和治疗组,对照组给予常规治疗,治疗组在常规治疗的基础上加用尤瑞克林,共14 d.两组治疗前后分别测血清CRP及IL-8浓度,并观察其神经功能缺损及残障程度评分变化.结果治疗后两组神经功能缺损及残障程度较治疗前均有改善,治疗组明显优于对照组(P<0.05);治疗后两组CRP及IL-8水平较治疗前均有所降低,治疗组较对照组显著降低(P<0.05).结论尤瑞克林对治疗ACI安全且有效,可显著降低急性脑梗死患者血清CRP及IL-8的浓度,对改善脑梗死病情有重要意义.Abstract: Objective To investigate the clinical curative effect of Urinary Kallidinogenase on the changes of serum C-reactive protein(CRP)and IL-8 in patients with acute cerebral infarction(ACI).Methods 66 acute cerebral infarction patients were randomly divided into two groups:treatment group and control group.Patients in both groups were given cerebral nervenutriceutical and antiplatelet routine treatment.Urinary Kallidinogenase was additionally used in the treatment group.The neurologic impairment scores and serum...
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Key words:
- Urinary KalIidinogenase /
- Acute cerebral infarction /
- C-reactive protein /
- IL-8
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