宫颈癌组织中Ki-67及Survivin的表达及其相关性研究
Clinical Research of the Expression and Correlation of KI-67 and Survivin in Cervical Carcinoma
-
摘要: 目的探讨Ki-67与Survivin在宫颈癌中的表达情况与宫颈癌临床特征的关系及其二者的相关性.方法采用免疫组化SP法检测KiI-67、Survivin在73例宫颈癌,25例宫颈上皮内瘤样病变(CIN)和20例慢性宫颈炎组织中的表达.结果从慢性宫颈炎组到宫颈癌组,Ki-67、Survivin表达率逐渐升高;Ki-67及Survivin的表达均与宫颈癌临床分期相关;Ki-67表达与Survivin表达呈正相关(r=0.671,P<0.01).结论 Ki-67、Survivin在宫颈癌组织中的表达情况,在一定程度上反映宫颈癌的恶性程度,与宫颈癌的分期及预后密切相关.Abstract: Objective To study the relationship between the expression of KI-67and Survivin in cervical carcinoma and the clinical feature of cervical carcinoma and to observe the correlation between KI-67 and Survivin in cervical carcinoma.Methods Using streptavidin-biotin peroxidase(SP)method,we examined the expression of KI-67and Survivin in 73 cases of cervical carcinoma,25 cases of cervical intraepithelial neoplasia(CIN)and 20 cases of chronic cervicitis.Results The expression of KI-67 and Survivin presented a gro...
-
Key words:
- Cervical carcinoma /
- Immunohistochemistry /
- KI-67 /
- Survivin
点击查看大图
计量
- 文章访问数: 2070
- HTML全文浏览量: 639
- PDF下载量: 26
- 被引次数: 0