复方地龙胶囊治疗2型糖尿病肾病的临床观察
A Clinical Investigation of Compound Dilong Capsule in the Treatment of Type 2 Diabetics Nephropathy
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摘要: 目的 探讨复方地龙胶囊对2型糖尿病肾病(DN)的临床疗效.方法 56例2型糖尿病肾病患者随机分为复方地龙胶囊治疗组30例和常规治疗对照组26例.治疗前后测定血液流变学和24 h尿蛋白定量水平.结果 与治疗前或常规治疗对照组比较,复方地龙胶囊组的24 h尿蛋白定量水平明显降低(P<0.05).与治疗前比较,复方地龙胶囊明显降低血小板最大聚集率(maximal platelet aggregation,PAgmax)、血浆粘度和全血粘度,对一时相血小板聚集率(first time platelet aggregation,PAgT1)和肌酐清除率(creatinine clearance rate,Ccr)水平无明显影响.治疗过程中未出现明显不良反应.结论 复方地龙胶囊能明显改善2型糖尿病肾病患者血液流变学指标,减轻尿蛋白的产生.Abstract: Objective To investigate the clinical value of compound Dilong capsule in the treatment of type 2 diabetics nephropathy.Methods 56 patients with type 2 diabetic nephropathy were randomly divided into compound Dilong group(n=30)and control group(n=26).Haemorheological parameters and total urine protein for 24 h were detected,respectively,before and after treatment.Results Compared with before treatment,the effective rate in compound Dilong capsule group was 85.6%,and 82.5% in the control group.There was no s...
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Key words:
- Type 2 diabetes /
- Compound dilong capsule /
- Haemorheology
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