妊娠糖尿病母、脐血脂联素水平的研究
Maternal and Umbilical Serum Adiponectin Levels of Women Suffering from Gestational Diabetes Mellitus
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摘要: 目的 研究妊娠糖尿病患者母、脐血脂联素水平变化,探讨脂联素在妊娠糖尿病发病机制中的作用.方法 采用口服50克葡萄糖-静脉血1 h血糖进行妊娠期糖尿病的筛查,静脉血-75克葡萄糖耐量试验行妊娠期糖尿病诊断.本研究采用ELISA法检测脂联素在16例妊娠期糖尿病患者(A组)、18例妊娠期糖耐量异常患者(B组)和35例糖耐量正常、同期分娩的正常妊娠妇女(C组)中母、脐血脂联素的浓度.结果 与B组及C组比较,A组母血脂联素浓度水平降低,差异有统计学意义(P<0.01);B、C组母血脂联素浓度水平比较,差异无统计学意义(P>0.05).浓度值分别为:A组(12.33±0.76) μg/mL,B组(15.31±1.84)μg/mL,C组(16.20±1.81) μg/mL.与B组及C组比较,A组脐血脂联素浓度水平降低,差异有统计学意义(P<0.01);B、C组脐血脂联素浓度水平比较,差异无统计学意义(P>0.05).浓度值分别为:A组(33.86±2.34)μg/mL,B组(45.72±1.69)μg/mL,C组(46.91±1.89)μg/mL.结论 妊娠糖尿病患者母血脂联素浓度降低;妊娠糖尿病患者脐血脂联素浓度降低;脐血脂联素浓度高于母血脂联素浓度.Abstract: Objective To investigate the concentration change of maternal and umbilical serum adiponectin from women suffering from gestational diabetes mellitus(GDM),and illustrate the role of adiponectin in pathogenesis of GDM.Methods GDM was diagnosed using 50 g glucose screening test followed by 75 g oral glucose tolerance test(OGTT).16 GDM cases(group A),18 GIGT cases(group B)and 35 cases of normal pregnant women with normal glucose tolerance delivered in the same period(group C)were included in this study.The con...
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Key words:
- Pregnancy /
- Diabetes /
- Adiponectin
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