髓鞘碱性蛋白在肺腺癌A549细胞表达及其功能意义
Functional Implication and Expression of MBP in Lung Adenocarcinoma Cells A549
-
摘要: 目的研究髓鞘碱性蛋白(MBP)在肺腺癌A549细胞中的表达及意义.方法用含10%胎牛血清的RPMI Medium1640培养基培养肺腺癌A549细胞,免疫组化SP法检测MBP在肺腺癌A549细胞的表达情况,探讨其功能意义.结果 MBP在A549细胞中的表达,以新生细胞为主,胞浆染色,阳性率约为21.1%.结论 MBP部分在肺腺癌A549细胞表达,这些新生细胞表达MBP形态可能与肺癌细胞的增殖能力或肺癌的嗜神经特性有关.Abstract: Objective To investigate the expression and its significance of myelin basic protein(MBP) in lung adenocarcinoma cells A549.Methods RPMI Medium 1640 with 10% fetal calf serum was used to culture lung adenocarcinoma cells A549,then the expression of MBP in lung adenocarcinoma cells A549 was detected by immunohistochemistry SP.Results Expression of MBP was mainly located in cytoplasm of lung adenocarcinoma cells A549,which exhibited a round shape,possibly as new cells.The positive rate of MBP positive cells w...
-
Key words:
- MBP /
- A549 /
- Lung Cancer
点击查看大图
计量
- 文章访问数: 2193
- HTML全文浏览量: 783
- PDF下载量: 26
- 被引次数: 0