BDNF在树鼩中枢神经系统的表达
BDNF Expression in the Central Nervous System of Tree Shrews(Tupaia Belangeri Chinensis)
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摘要: 目的观测脑源性神经营养因子(6rain-derived neurotrophic factor,BDNF)在树鼩中枢神经系统的表达.方法用RT—PCR技术探讨从胎儿、新生到成年过程中,观察树鼩中枢神经系统海马和脑干BDNF的表达变化.结果 BDNF在胎儿、新生和成年树鼩的海马和脑干均有表达,成年树鼩海马中的表达量显著高于胎儿和新生树鼩,差异有统计学意义(P<0.05).结论 BDNF在成年树鼩仍有较高的表达量.Abstract: Objective To detect BDNF expression in the central nervous system(hippocampus and brainstem) of tree shrews.Method RT-PCR was used to detect BDNF expression in the central nervous system(hippocampus and brainstem) of tree shrews from embryo to adult.Results BDNF expressed in hippocampus and brainstem of tree shrews from embryo to adult.The expression level of BDNF mRNA in adult was significantly higher than that of embryo and newborn tree shrews(P<0.05).Conclusion The expression level of BDNF is still high ...
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Key words:
- Tree shrew /
- BDNF /
- RT-PCR
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