短暂高水平呼气末正压肺复张对ARDS患者氧合和血液动力学的影响
Effect of Short-term High-level PEEP on Oxygen Metabolism and Hemodynamics in Patients with ALI/ARDS
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摘要: ［摘要］目的 研究短暂高水平呼气末正压（positive end expiratory pressure，PEEP）肺复张对急性呼吸窘迫综合征（acute respiratory distress syndrome，ARDS）患者氧合情况及血流动力学的影响．方法 40例患者被随机分为实验组（22例）和对照组（18例），实验组采用压力控制通气+短暂高水平呼气末正压肺复张，对照组采用压力控制通气，分别对两组患者的氧合、血流动力学及预后进行比较．结果 实验组氧合指标较对照组明显改善（P＜0.05）．结论 短暂高水平呼气末正压肺复张对于改善ARDS患者的氧合是安全有效的.Abstract: ［Abstract］Objective To study the effect of short-term high-level PEEP on oxygen metabolism and hemodynamics in patients with acute respiratory distress syndrome．Methods 40 cases with ALI/SRDS were randomly divided into study group （pressure control ventilation and short-term high-level PEEP， 22 cases） and control group（pressure control ventilation only，18 cases）．The changes of oxygenation，hemodynamics and prognosis of patients were compared between the two groups. Result After short-term high-level PEEP，there was a significant improving in PaO2，PaO2/FiO2 （P＜0.05） in the study group，but there was no significant difference in the the side effects and prognosis of patients．Conclusion Short-term high-level PEEP is effective and safe for patients with ALI/ARDS.
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