Abstract: ［Abstract］Objective　To investigate the clinical features and the diagnosis and treatment of colorectal cancer and intestinal obstruction．Method　The clinical data of 48 patients（2002.9－2010.9） with colorectal cancer and intestinal obstruction were retrospectively analyzed．Results　All of the 48 cases of colorectal cancer and intestinal obstruction underwent surgery．25 cases were incomplete preoperative obstruction before surgery，includingⅠresection anastomosis in 22 cases（right colon cancer obstruction in 8 cases，left colorectal cancer obstruction in 14 cases）， short-circuit operation in 1 case，palliative colostomy in 2 cases；23 cases were complete preoperative obstruction before surgery，includingⅠresection anastomosis in 5 cases（both right colon cancer obstruction），a proximal stoma afterⅠresection in 12 patients（six months after stoma back satisfied in 6 cases），palliative stoma in 6 cases．Postoperative anastomotic leakage occurred in 2 cases，1 case recovered after unobstructed drainage and parenteral nutrition suppor，1 gave up treatment，and died at five days after left the hospital；pulmonary infection was fund in 6 cases；wound infection in was 8 cases．Conclusion　Strengthening the understanding of colorectal cancer and intestinal obstruction， and choosing the timing of surgery and the surgical approach according to patients with specific conditions are the keys to improve the efficacy.