Abstract: ［Abstract］Objective　To sum up the clinical experience in the treatment of thoracolumbar burst fracture with transpedicular bone grafting，and to establish the specification of procedure in order to improve the safety and efficacy of the operation．Methods　Transpedicular bone（autogenous，allogenic，artificial calcium acid phosphate bone，artificial bone with BMP）grafting after reduction and fixation was given 60 cases of thoracolumbar burst fracture via posterior approach．X-ray and CT were performed post-operation．Results　Rod- broken was not found in all cases. The cavities were remained in two cases．The grafting bones were detected in the spinal canal in two cases．Fortunately，there was no symptoms of nerve injury．Four cases，the balloons were utilized to enlarge the cavity，were repletion of grafting bone．Conclusions　In the treatment of thoracolumbar burst fracture with transpedicular bone grafting，we should pay attention to the following details：The cases，the height and the back edge of vertebral body can be performed reduction perfectly，can be choosed to perform the operation；we advocate to use the cannula with debouch of 30 degrees；To control the cannula towards the cavity and the debouch towards the middle of vertebral body；The balloon for PKP is the better choice if the economic status of patient is permitted.