Objective　To study the issues concerning about the composition and organization of the teaching material on Medical Genetics，to analyze the application of new integration project of teaching material in teaching practice．Methods　Two class in Yunnan Medical College were divided into 2 groups，one of which（Study Group ）were taught according to the new integration project of teaching material and the other of which（Control Group）were taught according to the textbook's content sequence．After semester，grades for everyone and questionnaires were recorded and analyzed by mathematic statistics．Results　The studying achievement and interests of students were higher in the testing class which was taught according to the new integration project of teaching material than those in che control class which was taught according to the textbook's content sequence．Conclusion　The new integration project of teaching material from this thesis has high value in the field of theory and practice and can help to improve teaching effect of Medical Genetics.