昆明地区HIV/HCV共感染者不同CD4水平肝功能对比研究
Comparison of Liver Function in Patients with HIV/HCV Coinfection at Different CD4 T Cell Count Level in Kunming
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摘要: [摘要]目的 了解昆明地区HIV /HCV共感染患者进行高效抗逆转录病毒治疗(highly-active antiretroviral treatment,HAART)前不同CD4水平时的肝功能有无差别.方法 对昆明市第三人民医院感染科抗病毒治疗门诊进行HAART治疗的325例HIV/HCV共感染患者,于抗病毒治疗前进行肝功能水平及T淋巴细胞亚群检测.根据CD4水平的不同,分为CD4>200和CD4<200 2个组进行肝功能结果的比较.结果 HIV/HCV共感染者在CD4>200和CD4<200 2个组间比较,肝功能ALT 水平、AST水平、TBIL水平2组之间无统计学差异(P>0.05).结论 不同CD4水平时,HIV/HCV共感染患者的肝功能无明显影响
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关键词:
- [关键词]HIV/HCV /
- HAART /
- HCV
Abstract: [Abstract]Objectives To explore the difference of liver function in patients with HIV and HCV coinfection before HAART therapy at different CD4 level in Kunming.Methods 325 HIV/HCV coinfected patients before antiretroviral treatment were divided into two groups based CD4 T cell count:CD4>200 and CD4<200 group.To test the patients liver function,the serum ALT,AST,TBIL levels of the patients were detected.Comparison of liver function differences was made between two groups.Result There were no significant differences(P>0.05)in liver function between high and lower CD4 T cell count group.Conclusion There are no significant differeces in liver function between two groups of patients with HIV/HCV coinfection-
Key words:
- [Key words]HIV/AIDS;HCV;CD4;ALT /
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