Abstract: ［Abstract］Objectives　To provide some advice to the prevention and treatment of endemic dental fluorosis of Zhaotong by investigating the prevalence of dental fluorosis in high fluorine districe in Zhaotong．Methods　According to the basic methods of diagnostic criteria for dental fluorosis of the third national oral health epidemiological survey，a sample survey of dental fluorosis and oral health status were carried out．The samples were randomly gotten from the 12-year-old students and 35 - 44 year-old adults of local residents．In accordance with the respective proportions of 30% of the two groups for the questionnaire survey．Results　In 35-44 year old group，the detection rate of dental fluorosis was 100.0%， The dental fluorosis prevalence rate in 12 year-old students was 86.5%．Between the two groups there was a significant difference（P＜0.01，χ2 = 29.67）．The coal utilization rate and the baking food rate in urban areas were lower than in rural areas（P＜0.01）．The endemic fluorosis prevention and treatment knowledge rate was only 23.3%. 73.9% people thought dental fluorosis affecting their lives and aesthetics， and 91.1% of the population had an urgent treatment needs. 84.4% of the population had habit of brushing teeth， while 50.7% of the population still used fluoride toothpaste．Conclusions　After improving ovens to reduce fluoride pollution in high fluoride areas in Yunnan Zhaotong，the prevalence rate of DF decreased， but Zhaotong is still the moderate prevalent district．Besides improving ovens，the health education，scientific management，local economic and cultural levels also need to be improved.