Abstract: ［Abstract］Objective　To investigate the effect and toxicity of nedaplatin concurrent chemotherapy and radiotherapy on local advanced cervical Cancer．Methods　The nedaplatin was given at a dose of 30 mg（m2.w） once a week for 5 weeks in 35 patients. External radiotherapy was given at a dose 30 Gy firstly and then was irradiated for another 20 Gy under the condition of A point by linear accelerator 6Mev-X， the total radiotherapy dose was 50 Gy. From the 4th week post radiotherapy， intracavitary irradiation at DT 600cGy/time was given for twice a week， and lasted for 7 times to a total dose 4 200 cGy for A point. The curative effect and adverse reactions were observed．Results　The total effective rate and clinical benefits rate were both 89％．The 24 months disease-free survival and overall survival rate was 80％and 94％， respectively．Conclusion　Nedaplatin concurrent chemotherapy and radiotherapy can get better effects and tolerated side-effects