Abstract: ［Abstract］Objective　To explore the HIV/STD related potential risk factors in Vietnamese cross-border female sex workers，and to lay the foundation for the cross-border cooperation．Methods　We selected two fixed places of business in Hekou county，Yunnan province as survey sites．Census way was used to collect the data of Vietnamese cross-border female sex workers．Questionnaire survey and in-depth interview were used to collect data，including demographic characteristics，risk sexual behaviors，boss，whoremaster，language，companion and some other risk sexual behavior related influencing factors．Results　The AIDS infection rate was 5.9%，STD infection rate was 31.6% in Vietnamese cross-border female sex workers. The causes of not using condom were whoremasters' refuse or procuress' intervention．Meanwhile， language barrier， the competition with companion contributed to the incidence of risk sexual behaviors．Conclusions　Language barrier，the influence of companion， the manner of procuress and whoremaster are the potential risk factors to risk sexual behaviors in Vietnamese cross-border female sex workers．Chinese language training should be provided. Meanwhile，some intervention measures for procuress and whoremasters should be taken.