血栓抽吸导管在不稳定型心绞痛介入治疗术中无复流时的应用
Application of Thrombus Aspiration Catheter in Percutaneous Intervention Therapy for Unstable Angina with No-reflow Phenomeno
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摘要: 目的 分析不稳定型心绞痛高危患者在早期进行介入治疗时,球囊预扩张术后出现无复流时的治疗策略.方法 对比分析在早期进行介入治疗,球囊预扩张术后出现无复流现象时,选择药物治疗或药物治疗加血栓抽吸导管抽吸2种治疗方法之一进行治疗的32例不稳定型心绞痛患者,观察并记录2种治疗方法的血流TIMI分级、心肌灌注分级(MBG)、TIMI心肌灌注分级(TMP)等指标.结果 2组患者的基础和临床资料相似,使用药物治疗加血栓抽吸导管抽吸的患者,TIMI、MBG及TMP分级达到3级的患者比例为89%,使用药物治疗的患者,TIMI、MBG及TMP分级达到3级的患者比例为71%,2组比较差异有统计学意义(P<0.05).结论 在不稳定型心绞痛高危患者早期进行介入治疗,球囊预扩张术后出现无复流时,使用药物治疗加血栓抽吸导管抽吸更有助于提高心肌灌注水平.Abstract: Objective To analyze and summarize the treatment strategies for unstable angina with no-reflow phenomenon after PTCA during early percutaneous interventional procedures. Methods A total of 32 cases with unstable angina were divided into two groups: one group with drug therapy and the other group with drug therapy and thrombus aspiration catheter. The patients were chosen when there was no-reflow phenomenon after PTCA during early percutaneous interventional procedures and their clinical data were compared and analyzed. Blood flow TIMI grade, myocardial perfusion grade(MBG),TIMI myocardial perfusion(TMP) grade and other indexes were observed and recorded. Results The general conditions had no statistical difference between two groups. Compared with the drug therapy group,the proportion of patients with TIMI,MBG and TMP grade 3 was higher in aspiration and drug therapy group(89% VS 71% P<0.05). Conclusion Drug therapy and thrombus aspiration catheter in treatment helps to improve myocardial perfusion level for unstable angina with no no-reflow phenomenon after PTCA during early percutaneous interventional procedures.
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