昆明地区0～12岁儿童血浆25-(OH)D水平
Levels of 25-(OH)D in 0～12 years Old Children in Kunming
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摘要: 目的 了解昆明地区0~12岁儿童血浆25-(OH)D的水平和现状.方法 应用罗氏公司Roche cobas 8 000/E602全自动电化学发光免疫分析系统对昆明地区4区8县0~12岁4 489例儿童进行血浆25-(OH)D水平的检测,应用SPSS统计软件进行统计分析.结果 随着年龄的增大,血浆25-(OH)D浓度逐渐降低,各年龄组血浆浓度比较差异有统计学意义(P<0.05);男女2组血浆25-(OH)D浓度比较,结果差异无统计学意义(P>0.05);昆明地区儿童维生素D平均水平是83.48 nmol/L,0-1岁组儿童血浆25-(OH)D浓度呈分散性分布,6~9岁组血浓度分布最集中.结论 昆明地区0~12岁儿童维生素D水平总的处于一个良好的营养状况,但随着年龄的增长,维生素D营养水平逐渐降低,尤其3岁以后降低明显,均处于不足或缺乏状态,应引起大家的重视.Abstract: Objective To learn the levels of serum 25-(OH)D in 0~12 years old chindren in Kunming.Methods Serum 25-(OH)D levels of children(4 498) were measured by using Roche cobas 8 000/E602 automatic electrochemical luminescence immunoassay.Results As the increase of age,the levels of serum 25-(OH)D were gradually decreased,different age groups had significant difference(P<0.05).The levels of 25-(OH)D between boys and girls had no significant difference(P>0.05);The average level of sernm 25-(OH)D was 83.48 nmol/L,the level of serum 25-(OH)D was distributed in 0~1 years old group,and most concentrated in the 6~9 years old group.Conclusion The levels of 25-(OH)D in 0~12 years old chindren are in a good status,but with the increase of age,the level of 25-(OH)D is decreasing gradually, especially the levels of 25-(OH)D decreased significantly after the age of three, in shortage or lack of status, this should cause everybody's attention.
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