益生菌对老年冠心病患者血脂代谢的影响
Effect of Probiotics on Blood Lipid Metabolism of Elderly Patients with Coronary Heart Disease
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摘要: 目的 探讨老年冠心病(coronary heart disease,CHD)患者使用益生菌后,对脂质代谢的影响.方法 收集昆明医科大学附属延安医院2012年5月至2015年11月收治的100例老年CHD患者,随机分为观察组和对照组,各50例.所有患者常规给予CHD的二级预防用药,观察组加口服益生菌.观察治疗前和治疗12周后血脂水平变化的差异性.结果 观察组的血清总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)较对照组有明显改善,差异有统计学意义(P<0.05);高密度脂蛋白胆固醇(HDL-C)较对照组有明显提高,P<0.05.结论 益生菌辅助治疗老年CHD患者,可显著改善其血脂指标.Abstract: Objective To investigate the effect of probiotics on the blood lipid metabolism of elderly patients with coronary artery disease(CHD).Methods The clinical data of 100 elderly CHD patients who were admitted in our hospital from May 2012 ~November 2015 were collected.The enrolled patients were randomly divided into observation group and control group, 50 cases in each group.All patients were routinely given medication for secondary prevention of CHD,patients in the observation group were additionally given oral probiotics.Then we observed the changes in the lipid levels of patients before and after 12 weeks treatment.Results The serum total cholesterol(TC),triglyceride(TG),low density lipoprotein cholesterol(LDL-C) of patients in the observation group were improved more significantly than the control group,the difference was significant(P<0.05).The serum total High-density lipoprotein cholesterol(HDL-C) was improved more significantly than the control group.Conclusion Probiotics adjuvant therapy can significantly improve the blood lipid indexes in elderly CHD patients.
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Key words:
- Coronary heart disease /
- Probiotics /
- Lipid metabolism
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