Abstract: ［Abstract］Objective To explore the influential factors of pulmonary function in patients with chronic obstructive pulmonary disease（COPD）in Kunming district. Methods A total of 300 patients with COPD were selected from 5 tertiary hospitals in Kunming district as subjects investigated. The subjects were investigated by self-designed questionnaire，and then the influential factors of patients with COPD were analyzed. Results By linear correlation analysis, there were positive correlation between each of degree of education, economic income , the number of quitting smoking and percentage of the forced expiratory volume in one second divided by the predicted value（FEV1%pre）（r values respectively were 0.318，0.309，0.113，P values respectively were 0.000，0.000，0.05），there were negative correlation between smoking index，tobacco dependence score and FEV1%pre（r values respectively were -0.202，-0.323， P values respectively were 0.000，0.000）. By multiple linear regression analysis，FEV1%pre=34.792-1.765×tobacco dependence score+2.558×degree of education+2.587×economic income， in the nine influential factors（gender，age，body mass index， degree of education，economic income，smoking index，whether to give up smoking，number of quitting smoking， tobacco dependence score），the tobacco dependence score was the main factor affecting FEV1%pre. Conclusions The higher the degree of education，economic income of the patients with COPD have，the longer number of years of the patients with COPD quit smoking，the lower smoking index and tobacco dependence score tobacco dependence score have，the higher the FEV1%pre of the patients with COPD have. The tobacco dependence score is the main factor affecting FEV1%pre.