Abstract: ［Abstract］Objective　To explore a method to efficiently improve the diagnosis level of uterine dysplasia through a combination of a variety of methods, and compare its effect with other methods. Methods Three-dimensional ultrasonography and hysterosalpingography was performed in 65 patients with medical history of sterility，abortion，colporrhagia, premature birth and diagnosed with congenital Uterine dysplasia through transvaginal two-dimensional ultrasonography. Hysteroscope and laparoscope were also used in these patients with the comparison of their operative results. Results In 65 cases of patients with uterine dysplasia，there were 45 cases of mediastinal uterus，8 cases of arcuate uterus，5 cases of single Angle \ residual Angle uterus，4 cases of double uterus，2 cases of double Angle uterus, 8 cases of arcuate uterine, and 1 case of normal uterine cavity. Vaginal 3D imaging and hysteroscopy or laparoscopic surgery results were basically identical. Angiography in the diagnosis of uterine and uterine tubal iodine oil dysplastic type had limitations，mediastinum uterus was often misdiagnosed as single Angle's uterus，there were 8 cases of sample single Angle uterus and 1 case of double Angle uterus，difference was statistically significant （P < 0.05）. The diagnosis coincidence rate of transvaginal two-dimensional ultrasound for uterine dysplasia was lower, the difference was statistically significant（P < 0.05）. Conclusions The transvaginal three-dimensional ultrasonography is superior to transvaginal two-dimensional ultrasonography and hysterosalpingography technology in diagnosis of uterine malformation. And ultrasonic diagnosis could be regarded as the first choice because of its low cost and noninvasion, the combined application of various methods will improve the accuracy of diagnosis on uterine dysplasia.