Abstract: ［Abstract］Objective To evaluate the feasibility and safety of low atrial septum pacing， and investigate a simplified location methods for low atrial septum pacing. Methods Forty eight patients with pacemaker implantation standard，were randomly divided into two groups. Group A（n＝24）with low atrial septum pacing by active fixation electrode（LAS group），and group B（n＝24）with traditional right atrial appendage pacing by electrode passive fixation（RAA group）. The atrial electrode operating time， the success rate of implantation were recorded，and the pacing parameters were measured in first week，first months and third months after operation，and associated complications including electrode dislocation，pace pocket infection and blood，pericardial effusion was observed. Results　There were 21 cases success in atrial electrode location operation and 3 cases of failure in LAS group， while all operations were completed successfully in RAA group. Atrial electrode operation time had significant difference between two groups. The operate time of LAS group was longer than that of RAA group（6.3±0.8 min vs 3.5±0.5 min，P <0.05）. Pacing parameters remained stable during operation and on the first week，first and third months post-operative， and no significant differences existed between the two groups. No complications occurred during 3 months follow up. Conclusion The new simplified design technique of J shape duo-curve guide wire could increase the success rate of low atrial septum pacing. Low atrial septum pacing through active fixation electrode is safe and feasible.