Abstract: ［Abstract］Objective To investigate the clinical efficacy of 23-gauge transconjunctival sutureless vitrectomy （23G TSV） system in the treatment of vitreous hemorrhage. Methods 38 patients （43 eyes） underwent 23-gauge vitrectomy in our hospital from May 2013 to June 2015， and their clinical data were retrospectively analyzed. All patients were followed up 2 to 14 months after operation. We observed the best corrected visual acuity （BCVA），intraocular pressure（IOP）and postoperative complications. Results All cases were successfully performed and the postoperative BCVA had been improved. There were significant differences in BCVA between postoperative and preoperative（P < 0.05）. Few postoperative complications were observed， including cataract in 6 eyes， high IOP in 1 eye and low IOP in 3 eyes. However， all complications disappeared after a basic treatment. Conclusion 23G TSV system is an effective and safe surgical technique in the management of vitreous hemorrhage， which can improve the patients' visual and avoid the loss of visual function. It is worthy of clinical promotion.