Abstract: ［Abstract］Objective　To investigate correlation between level of serum uric acid（SUA）and brachial ankle pulse wave（baPWV）in essential hypertension（EH）with ischemic stroke（IS）patients．Methods　Forty-three patients with EH with IS，fifty-seven patients with EH and 49 normal subjects were selected randomly . All subjects were measured SUA and baPWV．we evaluated the association of SUA and baPWV in EH with IS patients．Results （1）The mean levels of Systolic blood pressure （SBP），diastolic blood pressure（DBP），Pulse pressure（PP）， the mean levels of SUA and baPWV were significantly higher in EH patients and EH with IS patients than control Patients ；the mean levels of SUA and baPWV in EH with IS patients were higher than EH patients（P＜0.05）.（2）After adjusting the factors of age，SBP，DBP，PP， triglyceride（TG）were still positively correlated（r = 0.451，P＜0.001） by partial correlation analysis.The multiple linear regression analysis showed that SUA and PP were the predictors of baPWV. Conclusion SUA is positively correlated with baPWV in patients with essential hypertension，and it can be used as an independent predictor. SUA is also the risk for patients with hypertension and stroke.