Abstract: ［Abstract］Objective　To study the application of coronary endarterectomy in surgical treatment of coronary heart disease，and to evaluate the early stage effect of CE plus CABG on patients with severe diffuse coronary artery stenosis. Methods Eighteen patients，who underwent coronary endarterectomy in our center and were followed up for 3 months between January 2013 and August 2015，were reviewed retrospectively and compared the group with 18 patients of their LV function，LVEDD，and cardiac function. Results Of all these 18 total coronary endarterectomies，6 cases（33.33%） were left anterior descending artery lesion，4 cases（22.22%）were diagonal branches lesion，4 cases（22.22%） involved the right coronary artery，3cases（16.67%）were posterior descending branches lesion， and 1 case（5.56%） were marginal branches lesion. Afer operation， all the patients recovered well in the early stage，without complications，LVEF and cardiac function improved significantly， LVEDD reduced significantly，compared with themselves preoperativly（P > 0.05）. Conclusion Cornary endarterectomy is an effective treatment for patients with diffuse coronary artery disease. This procedure will improve cardiac function and take a turn for the worse cardiac remodeling for patients with diffuse coronary artery disease.