Abstract: ［Abstract］Objective　To investigate the improvement and safety of the conventional treatment combined with Deanxit in the treatment of digestive adverse（FD）of gastrointestinal symptoms and sleep efficacy. Methods　Ninety cases of patients with FD were randomly divided into the control group（pantoprazole capsule and Mosapride will + Capsule associated with sleep disorders with estazolam tablets）and observation group （pantoprazole capsule and Mosapride will + capsule with sleep disorders and estazolam tablets plus Deanxit）. Both groups were treated for 4 weeks. After the course of treatment， the improvement degree and adverse reaction of digestive tract symptoms and sleep were compared between the two groups．Results　After 4 weeks of treatment in the observation group with gastrointestinal symptoms were improved and the total effective rate was 86.7%，higher than that of the control group（66.7%）.The difference was statistically gigmificart（P < 0.05）. The total effective rate of was sleep disorders improvement 83.3%， higher than that of control group（61.9%），but the difference was not statistically significant （P > 0.05）.Adverse reaction rates were not significantly different between the two groups. Conclusion　On the basis of conventional therapy，treatment of functional dyspepsia （FD）with Deanxit can significantly alleviate gastrointestinal symptoms．Medication after 3-7 days can relieve the symptoms. After 4 weeks， the total efficiency is the highest with fewer adverse reactions．Clinical application is recommended.