Abstract: ［Abstract］Objective　To observe exposure rates of hydroxyapatite artificial eye by comparing hydroxyapatite prosthesis implantation through lateral rhinotomy approach on the orbit and traditional sclera shell hydroxyapatite prosthesis implantation．Methods　After eye content was enucleated at postoperative stage I， 75 patients received hydroxyapatite prosthesis implantation，among which 26 received direct sclera shell prosthesis implantation （group A） and 49 received implantation through lateral rhinotomy approach on the orbit （group B）. During postoperative follow-up from 6 months to 5 years，exposure rates of hydroxyapatite artificial eye under two operation ways were observed and analyzed by χ2 test．Results　According to observation，8 cases were exposed in the group A，and 2 cases were repaired by fascia and conjunctival repair．Six cases were healed by prosthesis and sclera replacement．In group B，only 1 case was exposed slightly and recovered after simple conjunctival repair. The incidence of the eye exposure rate using two kinds of operation methods in group A is significantly higher than that in group B（P < 0.05）．The difference was statistically significant. Conclusion　The exposure of hydroxyapatite artificial eye can be effectively avoided and postoperative complications can be reduced by hydroxyapatite prosthesis implantation through lateral rhinotomy approach on the orbit among patients with severe eyeball ruptures，painful eyeballs of no light perception and atrophy eyes.