Abstract: ［Abstract］Objective　To analyze the application of human blood albumin among patients with traumatic fracture. Methods　A retrospective analysis was conducted in 86 patients with hypoalbuminemia after traumatic fracture from December 2013 to May 2014 in our hospital，including 43 patients with closed fractures and 43 patients with open fracture. To observe the curative effect，patients with closed fracture and open fracture were divided into the treatment group and the control group respectively according to the use of human albumin. Results Among the patients with closed fracture in the therapeutic group and the control group，wound healing time，soft tissue swelling fade time，white blood cell count， neutrophil percentage， c-reactive protein and wound infection rates were compared and no significant differences were seen（P＞0.05）. In terms of the treatment of open fractures， the observed indicators showed statistical significance after the application of human blood albumin compared with the control group（P＜0.05）. Conclusion　Not all the patients with hypoalbuminemia after traumatic fractures are suitable for the application of human blood albumin at the first place. Advantages are seen among patients with hypoalbuminemia after open fractures when they are applied with human blood albumin. Human blood albumin can promote postoperative recovery of the fractures and reduce the risk of infection，which is worthy of popularization and application.