Abstract: ［Abstract］Objective　To evaluate the clinical efficacy of Tanreqing injection combined with ganciclovir in the treatment of pediatric respiratory syncytial virus pneumonia. Methods　Ninety cases of children with respiratory tract virus pneumonia were selected in our hospital from August 2014 to December 2015， and were randomly divided into observation group and control group，and 45 cases in each group. The control group was given conventional anti infection，expectorant and antiasthmatic，antipyretic，atomization inhalation symptomatic and supportive treatment，on this basis the ganciclovir injection；the observation group was additionally given Tanreqing treatment on the basis of the control group. Then we compared the effects of two groups，pulmonary rales， wheezing，cough disappeared time， hospitalization time and the incidence of adverse reactions. Results　After the treatment，the total efficiency of the observation group （93.3%） was significantly higher than that of control group （75.6%），the difference was statistically significant （P < 0.05）. The pulmonary rales （5.58 + 1.41），cough （5.78 + 1.61），wheezing（3.45 + 0.87）disappear time and hospital stay time（5.34± + 0.61）of patients in the observation group was significantly shorter than that of the control group（6.93 + 1.61，7.73 + 1.65，479 + 1.02， 736，0.52），and the difference was statistically significant（P < 0.05）. The adverse reaction incidence in the observation group（20.0%）and the control group（22.2%）had no statistically significant difference（P > 0.05）. Conclusion　Tanreqing injection combined with ganciclovir in the treatment of children with respiratory syncytial virus pneumonia has good efficacy and less adverse reactions， it is worthy of further research and application in clinic.