VASP信号分子与大肠癌的关系
The Relationship of VASP Signaling Molecule and Colorectal Cancer
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摘要: [摘要]大肠癌发生发展与GCC/PKG/VASP、PKA/VASP等信号通路有关,VASP作为其中的一个重要的信号分子,在大肠癌的凋亡、侵袭转移、血管生成等过程中起到了重要作用.就VASP信号分子及相关的信号通路在大肠癌发生发展中的作用及其潜在临床意义进行综述.Abstract: [Abstract]GCC/PKG/VASP,PKA/VASP et.al are associated with the occurrence and development of colorectal cancer. As one of the important signaling molecules of above signal pathways,VASP has constributed to the invasion,metastasis,apoptosis,angiogenesis and other events of colorectal cancer. The role of VASP signaling pathways in the development of CRC and its potential clinlic significance are reviewed in this article.
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