Abstract: Objective To analyze the results of HIV/AIDs surveillance among the men who have sex with men(MSM) in Guandu District, Kunming City, so as to provide the evidence for the future development of prevention and control strategies. Methods We analyzed the infection of HIV,syphilis and hepatitis C and related behaviors.Results A total of 462 MSM were surveyed in 2013-2015,the total HIV positive rate was 15.8%(73 cases),and the HIV positive rate was 16.2%,15.4%,16.1% in 2013,2014 and 2015,respectively,there was no statistically deference between three years(P >0.05).There were 50 cases(10.8) of syphilis antibody positive,one case(0.2%) of HCV antibody positive. In the last six months, there were 95.7% who had anal sex, among them there were 56.5% who used condom every time,there were 83.5% who used condom in last anal sex;there were 15.2% who had commercial sex with MSM, among them there were 58.2% who used condom every time;there were 21.9% who had sex with women, among them there were 40.6% who used condom every time. Conclusions The awareness rate of HIV/AIDS was high, but the condom use rate was low,there was a discrepancy between their knowledge and their behavior. The HIV positive rate and syphilis antibody positive rate were high,the prevention and control condition is very serious, we should take actions to improve our intervention strategies.