应力下髁突软骨中相关因子对髁突生长发育作用的研究进展
Research Progress in the Effects of Cytokines in Condylar Chondrocyte on Condylar Development under Mechanical Loading
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摘要: 髁突生长发育和代谢受到力学刺激的影响,以维持软骨内细胞及基质新陈代谢平衡,保障颞下颌关节正常的形态和功能.这个适应性改建过程依赖于软骨细胞对各种机械化学信号刺激的应答反应.就参与髁突软骨力学信号转导的一些重要因子研究进展作一综述.Abstract: The growth and development of condyle is affected by the mechanical stress stimulation, which maintains the balance of condylar chondrocytes and extracellular matrix metabolism, as well as the structure and function of the temporomandibular joint. The adaptive remodeling relies on the mechanical signals response of the chondrocytes. This review aims to discuss about some of the main factors related to the mechanical stress signal transduction of the condylar chondrocytes.
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Key words:
- Condylar chondrocyte /
- Mechanical loading /
- Cytokine
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