兰索拉唑在胃食管反流患者中的临床效果及对食管动力学的影响
Clinical Effect of Lansoprazole on Patients with Gastroesophageal Reflux and the Esophageal Dynamics
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摘要: 目的 观察兰索拉唑在胃食管反流患者中的临床效果及对食管动力学的影响状态.方法 选取2015年10月至2016年8月期间曲靖市第一人民医收治的76例胃食管反流患者为研究对象,将76例患者随机分为对照组(奥美拉唑组)38例和观察组(兰索拉唑组)38例,然后将2组患者治疗后的总有效率、治疗前后的症状体征评分及食管动力学指标进行统计学处理.结果 观察组治疗后的总有效率显著地高于对照组(P<0.05),治疗前2组患者的症状体征评分及食管动力学指标差异无统计学意义(P>0.05),而治疗后观察组的症状体征评分及食管动力学指标均好于对照组(P<0.05).结论 兰索拉唑在胃食管反流患者中的临床效果较好,且可改善此类患者的症状体征及食管动力学状态,有临床应用价值.Abstract: Objective To observe the clinical effect of lansoprazole on the patients with gastroesophageal reflux and the influence on the esophageal dynamics. Methods Seventy-six patients with gastroesophageal reflux in our hospital from October 2015 to August 2016 were set as the study object,and 76 patients were randomly divided into control group(omeprazole group) and observation group(lansoprazole group),38 cases in each group,then the total effective rates,symptoms and signs score and esophageal dynamics indexes of patients in two groups before and after the treatment were respectively analyzed. Results The total effective rate of observation group was significantly higher than the rate of control group(P<0.05),the symptom and sign score and esophageal dynamics indexes of two groups before the treatment had no significantly differences(P>0.05),while the symptom and sign score and esophageal dynamics indexes of observation group after the treatment were all better than those of control group(P<0.05).Conclusion The clinical effect of lansoprazole in the patients with gastroesophageal reflux is better,and it can significantly improve the symptoms and signs and esophageal dynamics state,so its clinical application value is higher.
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Key words:
- Lansoprazole /
- Gastroesophageal reflux /
- Clinical effect /
- Esophageal dynamics
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