云南省不同地区3~18岁人群先天性心脏病流行病学特征调查
Epidemic Characteristics of Congenital Heart Disease of Adolescents between 3 to 18 ages Among Different Regions in Yunnan
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摘要: 目的 了解云南不同地区318岁少年儿童先天性心脏病的患病现状和分布特征.方法 采用整群抽样的方法, 分别对云南省丽江、迪庆、巧家3个地区, 共34 349名318岁少年儿童, 开展先天性心脏病流行病学调查.结果 调查地区先天性心脏病总患病率为7.65‰ (262/34 349) , 不同性别患病率差异有统计学意义 (χ2=4.338, P=0.037) , 其中男性为6.72‰, 女性为8.71‰;不同年龄组患病率差异有统计学意义 (χ2=9.622, P=0.022) , 37岁年龄组最高为11.94‰;不同地区患病率差异无统计学意义 (χ2=1.761, P=0.415) , 丽江为6.13‰, 迪庆为8.09‰, 巧家为7.68‰;不同民族患病率差异有统计学意义 (χ2=14.374, P=0.013) , 汉族为7.58‰, 藏族为5.32‰, 纳西族为7.95‰, 傈僳族为11.94‰, 彝族为10.24‰, 其他为10.68.结论 调查地区先天性心脏病患病率高于全国平均水平, 女性患病率明显高于男性, 37岁年龄组患病率最高, 不同地区患病率无差异, 患病类型以房间隔缺损为主.Abstract: Objective To learn the status of the prevalence and distribution characteristics of congenital heart disease (CHD) of adolescents between 3 to 18 ages among different regions in Yunnan. Methods From January 2013 to November 2014, the epidemic survey of CHD was carried out in regions of Lijiang, Diqing and Qiaojia by cluster sampling.Results The total prevalence rate of CHD was 7.65‰ in 34349 adolescents investigated in this research. However, the morbidity rate in female patients was 8.71‰, and male 6.72‰, the difference had statistical significance (χ2=4.338, P=0.037) ; the difference among different age groups had statistical significance (χ2 =9.622, P =0.022) , and 3 7 age group was the highest 11.94‰; the difference among three regions, Lijiang, Diqing, Qiaojia (6.13‰, 8.09‰, 7.68‰ respectively) had no statistical significance (χ2 =1.761, P =0.415) ; the difference among ethnic groups, the Han, Tibetan, Naxi, Lisu, Yi nationality and the others, had statistical significance (χ2 =14.374, P =0.013) .Conclusions The prevalence of CHD in investigated regions is higher than the average level of the nationwide, is obviously higher in female group than male group, is the highest in the group of 3 7 age, the difference among three regions has no statistical significance. The main kind of CHD is atrial septal defect (ASD) .
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Key words:
- Congenital heart disease /
- Cross-sectional study /
- Prevalence rate
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[1]李顺辉, 颜友良, 童一帆, 等.江西省3~14岁儿童先天性心脏病流行病学调查[J].中国当代医药, 2015, 7 (28) :174-176+179. [2]高莉洁, 赵仲堂, 李栋, 等.先天性心脏病环境危险因素病例对照研究[J].中国公共卫生, 2005, 21 (2) :161-162. [3]高秉仁, 岳凤珍.甘肃省六地市先天性心脏病流行病学调查研究[J].中国循环杂志, 2000, 15 (5) :298-299. [4]蒋立虹, 段昌群, 马志强, 等.云南省部分地区3-18岁人群先天性心脏病患病率调查[J].中华流行病学杂志, 2005, 26 (3) :182-186. [5]刘锦桃, 刘群娟, 李赛玲, 等.昆明市3~17岁儿童先天性心脏病流行病学调查[J].中国优生与遗传杂志, 2000, 8 (2) :5-7. [6]王军, 王志农, 李素芝, 等.拉萨市6500名小学生先天性心脏病调查[J].西藏科技, 2002, 105 (1) :12-14. [7] [7]YANG XY, LI XF, LU XD, et al.Incidence of congenital heart disease in Beijing, China[J].Chin Med J (Engl) , 2009, 35 (122) :1128-1132. [8]刘瑞昌, 吴天一, 格日力, 等.青海高原儿童先天性心脏病调查[J].中华心血管病杂志, 1982, 10 (4) :241-242. [9] 金新会, 陈秋红, 童有福, 等.青海省不同海拔高度地区4~18岁藏族少年儿童先天性心脏病流行病学调查[J].中华流行病学杂志, 2008, 29 (4) :317-320. [10]刘小清, 麦劲状, 高向民, 等.广东省中西南北部地区婴儿先天性心脏病的发病状况分析[J].中华心血管病杂志, 2013, 41 (4) :337-340. [11]贾明, 胡文莉, 周晔, 等.静脉注射地尔硫治疗先天性心脏病合并重度肺动脉高压[J].中华心血管病杂志, 2006, 34 (5) :400-402. [12]赵光敏, 王福, 王德明, 等.白族地区13821名学龄儿童先天性心脏病流行病学调查[J].中国循环杂志, 1991, 6 (4) :301. [13]胡盛寿, 李守军, 张浩, 等.介入技术和外科手术同期"复合"治疗先天性心脏病的临床研究[J].中华心血管病杂志, 2006, 34 (3) :236-239. [14] [14]MALIK S, SCHECTER A, CANGHY M, et a1.Effect of proximity to hazardous waste sites on the development of congenital heart disease[J].Arch Environ Health, 2004, 59 (4) :177-181. [15]赖小今, 李树森, 刘宝玉, 等.成都地区先天性心脏病相关因素流行病学研究[J].四川医学, 2005, (12) :1384-1386. [16] [16]DADVAND P, RANKIN J.SHIRLEY M D, et al.Descriptive Epidemiology of congenital heart disease in Northern England[J].Paediatr Perinat Epidemiol, 2008, 41 (23) :58-65. [17] [17]WU T, LI S, WARD MP.Tibetans at extreme altitude (Review) [J].Wilderness Environ Med, 2005, 29 (16) :47-54. [18]华静, 孟灿, 贾贤杰, 等.先天性心脏病危险因素1:1配对病例对照研究[J].上海交通大学学报, 2010, 30 (8) :894-896. [19]刘晓康, 桑灏, 修剑峰, 等.四川省凉山州在校学生先天性心脏病患病调查[J].中华内科杂志, 2013, 52 (6) :494-496. [20] 陈秋红, 路霖, 徐效龙, 等.青海省海东地区三县4~18岁人群先天性心脏病的流行病学调查[J].中华预防医学杂志, 2009, 43 (4) :319-321. [21]曹霖, 夏洪韬, 龚宇, 等.先天性心脏病手术患儿ICU住院时间延长的危险因素分析[J].川北医学院学报, 2012, 27 (06) :604-608. [22]赵光临, 代礼, 谢建生, 等.深圳市先天性心脏病流行病学特征研究[J].中国妇幼保健, 2013, (22) :3633-3636. [23]许愿愿, 张伟华, 左明鲜, 等.先天性心脏病介入治疗855例临床疗效分析[J].昆明医学院学报, 2010, 31 (8) :131-133 [24]姚慧.先天性心脏病有关危险因素研究进展[J].中国健康教育, 2014, 18 (7) :637-640. [25]闫明亮, 蒋立虹, 侯宗柳.云南省3551例先心病患者的ABO血型及性别分析[J].昆明医学院学报, 2012, 33 (4) :56-59.
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