常用非离子型碘对比剂过敏反应分析及护理对策
Analysis of the Allergic Reaction and Nursing Measures of the Commonly Used Non Ionic Iodine Contrast Agent
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摘要: 目的 分析总结临床常用的非离子型碘对比剂过敏反应及护理措施.方法 2012年1月至2015年12月间注射非离子型碘对比剂24 h内发生过敏反应170例, 对对比剂种类、浓度、流速等因素及护理措施进行分析.结果 碘普罗胺、碘海醇、碘帕醇总的不良反应发生率分别为0.38%、0.35%、0.44%, 碘帕醇总的不良反应发生率稍高于碘普罗胺和碘海醇, 3种药物间差异无统计学意义 (P>0.05) .碘普罗胺组发生过喉头水肿、敏性休克发生率为分别为十万分之七、千分之三, 为罕见不良反应.结论 少部分患者使用非离子型碘对比剂会出现不同程度的过敏反应, 应小心谨慎, 加强护理, 保障碘对比剂的临床用药安全.Abstract: Objective To summarize the allergic reaction and nursing measures of clinical commonly used non ionic iodine contrast agent.Methods Between May 2012 and December 2015, 170 cases of allergic reactions occurred within 24 hours after the injection of nonionic iodine contrast agent.The factors, such as the type, concentration and flow rate of the contrast agents, and the nursing measures were analyzed.Results The incidence of total adverse reactions of iopromide, iohexol, and iopamidol were 0.38% and 0.35%, 0.44%, respectively.The total adverse reactions rate of iopamidol was slightly higher than the iopromide and iohexol, the three drugs had no statistical difference (P > 0.05) .The incidence of laryngeal edema and allergic shock in iopromide group were seven in one hundred thousand and three in thousand, rare adverse reactions.Conclusion A small part of patients who used non ionic iodine contrast agent may appeare allergic reactions in different degrees, so we should be careful, strengthen the care, gurrantee the clinical drug safety of iodine contrast agent.
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Key words:
- Nonionic iodine contrast agent /
- Allergic reaction /
- Enhanced scan
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[1]李朝晖, 马晓鹂, 官堂明.碘普罗胺注射液不良反应的文献计量分析[J].今日药学, 2014, 24 (6) :412-414.[1]李朝晖, 马晓鹂, 官堂明.碘普罗胺注射液不良反应的文献计量分析[J].今日药学, 2014, 24 (6) :412-414. [2] 中华医学会放射学分会, 中国医师协会放射医师分会对比剂使用指南[J].中华放射学杂志, 2008, 42 (3) :320-325.[2]中华医学会放射学分会, 中国医师协会放射医师分会对比剂使用指南[J].中华放射学杂志, 2008, 42 (3) :320-325. [3] [3]NAMASIVAYAM S, KALRA M K, TORRES W E, el al.Adverse reactions to intravenous iodinated contrast media:a primer for radiologists[J].Emerg Radiol, 2006, 12 (5) :210-215.[3]NAMASIVAYAM S, KALRA M K, TORRES W E, el al.Adverse reactions to intravenous iodinated contrast media:a primer for radiologists[J].Emerg Radiol, 2006, 12 (5) :210-215. [4]张保翠, 张玉东, 赵凯, 等.静脉注射碘对比剂对不同人群肾功能的影响[J].中华放射学杂志, 2013, 47 (4) :335-339.[4]张保翠, 张玉东, 赵凯, 等.静脉注射碘对比剂对不同人群肾功能的影响[J].中华放射学杂志, 2013, 47 (4) :335-339. [5] 中华医学会放射学分会对比剂安全使用工作组.碘对比剂使用指南 (第2版) [J].中华医学杂志, 2014, 94 (43) :3363-3369.[5]中华医学会放射学分会对比剂安全使用工作组.碘对比剂使用指南 (第2版) [J].中华医学杂志, 2014, 94 (43) :3363-3369. [6]吴雷, 李国晖, 杨燕, 等.高压注射器联合静脉留置针在CT血管造影评价兔脑血栓模型中的应用[J].重庆医学, 2014, 43 (31) :4179-4184.[6]吴雷, 李国晖, 杨燕, 等.高压注射器联合静脉留置针在CT血管造影评价兔脑血栓模型中的应用[J].重庆医学, 2014, 43 (31) :4179-4184. [7] [7]Hartman GW, Hattery RR, Witten DM, et a1.Mortality during excretory urography:Mayo Clinic experience[J].Am J Roentgenol, 1982, 139 (5) :919-922.[7]Hartman GW, Hattery RR, Witten DM, et a1.Mortality during excretory urography:Mayo Clinic experience[J].Am J Roentgenol, 1982, 139 (5) :919-922. [8]王彤春, 杜文民, 王宏敏.非离子型含碘对比剂不良反应Logistic回归分析[J].药物流行病学杂志, 2008, 17 (3) :167-169.[8]王彤春, 杜文民, 王宏敏.非离子型含碘对比剂不良反应Logistic回归分析[J].药物流行病学杂志, 2008, 17 (3) :167-169. -
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