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改良抗酸染色法检测胸腔积液中结核分枝杆菌对结核性胸膜炎的诊断

窦权利 周九鹏 杨元利 张永峰 党丽云 孙惠平

窦权利, 周九鹏, 杨元利, 张永峰, 党丽云, 孙惠平. 改良抗酸染色法检测胸腔积液中结核分枝杆菌对结核性胸膜炎的诊断[J]. 昆明医科大学学报, 2017, 38(09): 35-38.
引用本文: 窦权利, 周九鹏, 杨元利, 张永峰, 党丽云, 孙惠平. 改良抗酸染色法检测胸腔积液中结核分枝杆菌对结核性胸膜炎的诊断[J]. 昆明医科大学学报, 2017, 38(09): 35-38.
Dou Quan Li , Zhou Jiu Peng , Yang Yuan Li , Zhang Yong Feng , Dang Li Yun , Sun Hui Ping . Diagnostic Value of a Modified Acid-fast Staining Protocol for Mycobacterium Tuberculosis Detection in Pleural Fluid Samples from Patients with Tuberculouspleuritis[J]. Journal of Kunming Medical University, 2017, 38(09): 35-38.
Citation: Dou Quan Li , Zhou Jiu Peng , Yang Yuan Li , Zhang Yong Feng , Dang Li Yun , Sun Hui Ping . Diagnostic Value of a Modified Acid-fast Staining Protocol for Mycobacterium Tuberculosis Detection in Pleural Fluid Samples from Patients with Tuberculouspleuritis[J]. Journal of Kunming Medical University, 2017, 38(09): 35-38.

改良抗酸染色法检测胸腔积液中结核分枝杆菌对结核性胸膜炎的诊断

基金项目: 

基金: 陕西省科技惠民计划基金资助项目 (2013K14-02-30);

Diagnostic Value of a Modified Acid-fast Staining Protocol for Mycobacterium Tuberculosis Detection in Pleural Fluid Samples from Patients with Tuberculouspleuritis

Funds: 

基金: 陕西省科技惠民计划基金资助项目 (2013K14-02-30);

  • 摘要: 目的 评价改良抗酸染色法在结核性胸膜炎的诊断价值.方法 选取2013年10月至2015年02月于西安市胸科医院诊治的胸腔积液患者, 纳入实验组即结核性胸腔积液115例, 对照组恶性胸腔积液36例, 分别应用改良的抗酸染色法、传统的Ziehl-Neelsen染色法、BACTEC-MGIT 960培养检测, 将BACTEC-MGIT 960培养结果作为参考标准, 确定两种染色方法的灵敏度和特异性.结果 以培养结果作为参考标准, 改良染色法的灵敏度, 特异度, 阳性预测值 (PPV) , 和阴性预测值 (NPV) 分别为72.2%, 100%, 100%, 和52.9%;传统染色法分别为0, 100%, 0, 和23.8%.结论 改良抗酸染色法可明显提高结核性胸膜炎的阳性诊断率, 具有简便、快速、准确的优点, 能为结核性胸膜炎的诊断提供病原学依据, 值得临床推广应用.
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