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合并桥本氏甲状腺炎的甲状腺癌外科治疗

李磊 杨洁 王伟霖 王虎

李磊, 杨洁, 王伟霖, 王虎. 合并桥本氏甲状腺炎的甲状腺癌外科治疗[J]. 昆明医科大学学报, 2017, 38(10): 95-100.
引用本文: 李磊, 杨洁, 王伟霖, 王虎. 合并桥本氏甲状腺炎的甲状腺癌外科治疗[J]. 昆明医科大学学报, 2017, 38(10): 95-100.
Li Lei , Yang Jie , Wang Wei Lin , Wang Hu . Surgical Treatment Strategy of Thyroid Carcinoma with Hashimoto's Thyroiditis[J]. Journal of Kunming Medical University, 2017, 38(10): 95-100.
Citation: Li Lei , Yang Jie , Wang Wei Lin , Wang Hu . Surgical Treatment Strategy of Thyroid Carcinoma with Hashimoto's Thyroiditis[J]. Journal of Kunming Medical University, 2017, 38(10): 95-100.

合并桥本氏甲状腺炎的甲状腺癌外科治疗

基金项目: 

基金: 云南省卫生科技计划资助项目 (2012WS0035);

Surgical Treatment Strategy of Thyroid Carcinoma with Hashimoto's Thyroiditis

Funds: 

基金: 云南省卫生科技计划资助项目 (2012WS0035);

  • 摘要: 目的 探讨甲状腺乳头状癌 (papillary thyroid carcinoma, PTC) 合并桥本氏甲状腺炎 (hashimoto’s thyroiditis, HT) 的临床特点及手术策略.方法 回顾性分析334例PTC患者以及其中合并HT的患者临床病理资料.结果 单纯PTC组 (252例) , PTC合并HT组 (82例) , 所有患者均行手术治疗, 根据患者病情分别行腺叶+峡部切除、全切或近全切除以及不同范围的颈淋巴结清扫术, 术后病理证实为PTC.与单纯PTC组比较, PTC合并HT组中女性所占比、单叶受累、颈淋巴结阴性比率均明显增加, 而病灶最大径明显减小 (P<0.05) .发现单纯PTC组较PTC+HT组有更高的中央区淋巴结转移率 (P=0.001) , HT合并PTC组发生术后低钙的比率明显增高.结论 甲状腺乳头状癌 (PTC) 合并桥本氏甲状腺炎以女性多见, HT可能对PTC原发灶的外侵、腺体内及颈部淋巴结转移有一定的抑制作用, 合并HT的甲状腺癌手术术后并发症增加, 值得引起注意.
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  • 收稿日期:  2017-04-21

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