器官移植与口腔疾病的关系
Relationship between Organ Transplantation and Oral Diseases
-
摘要: 器官移植作为终末期器官衰竭的常规治疗方法, 已广泛运用于临床.移植后患者机体的改变及免疫抑制剂的运用, 导致口腔病损发生.口腔内存在的感染成为移植术后患者发生局部和全身感染的潜在风险.对器官移植与口腔疾病的相互影响关系以及移植术前的口腔准备及术后护理作一综述.Abstract: Organ transplantation as a routine treatment of end-stage organ failure has been widely used in clinical practice.Changes in the body after transplantation and the use of immunosuppressive agents, leading to oral lesions occurred.The presence of infection in the oral cavity becomes a potential risk of systemic and local infection in patients after transplantation.This article summarizes the relationship between organ transplantation and oral diseases and oral preparation before surgery and postoperative oral care.
-
Key words:
- Organ transplantation /
- Oral disease /
- Oral care
-
[1]韦艺, 周嫣.环保菌素A引起牙龈增生的机制研究现状[J].中国临床新医学, 2012, 5 (1) :78-80. [2] [2]LINSKUSTERER L E F.Oral diseases and liver pre and posttransplantationdisorders[J].J Transplant Technol Res, 2012, 2 (S1) :001. [3] [3]RATERITS CHAK-PLUSS E M, HEFTI A.Initial observation that cyclosporin-A induces gingival enlargement in man[J].J Clin Periodontol, 1983, 10 (3) :237-246. [4] [4]TOMASON J M, SEYMOUR R A, ELLISHJS.Risk factors for gingival overgrowth in patients medicated with ciclosporin inabsence of calcium channel blockers[J].JClin Periodontol, 2005, 32 (3) :273-279. [5] [5]TIPTON D A, STRICKLIN G P, DABBOUS M K.Fibroblast heterogeneity in collagenolytic response to cyclosporine[J].J Cell Biochem, 1991, 46 (2) :152-165 [6] [6]BULLON P, MACHUCA G, MARTINEZ-SAHUQUILLO A, et al.Clinical assessment of gingival hyperplasia in patients heated with nifedipine[J].J Clin Periadontol, 1994, 21 (4) :256-259. [7]曹颖光, 李明, 刘慎微.环抱素A导致牙龈增生的调查分析[J].中华器官移植杂志, 2003, 24 (1) :31-32. [8]丁树湘, 佟锦.器官移植的新问题--口腔粘膜溃疡及坏疽[J].现代口腔医学杂志1987, 1 (1) :57-58. [9] [9]DONGARI-BAGTZOGLOU, DWIVEDII, IOANNIDOU.Oral candida infection andcolonization in solid organtransplant recipients[J].Oral Microbiol Immunol, 2009, 24 (3) :249-254. [10] [10]DONGARI-BAGTZOGLOU A, FIDEL PL J R.Thehost cytokine responses and protectiveimmunity in oropharyngeal candidiasis[J].J Dent Res, 2005, 84 (11) :966-977. [11] [11]GOLECKA M, MIERZWIN E SKA-NASTALSKA, et al.Influence of oral hygiene habits on prosthetic stomatitis omplicated by mucosal infection 11 after organ transplantation[J].Transplantation Proceedings, 2007, 39 (9) :2875-2878. [12] [12]JAANA HELENIUS-HIETALTA, HELLEVI RUOKOEN, LISA GR ONROOS.Oral mucosal health in liver transplant recipients and controls[J].Liver Transpl, 2013, 20 (1) :72-80. [13]张志霞, 刘瑶, 周泽渊.器官移植术后口腔病变与防治[J].实用口腔医学杂志, 2007, 23 (3) :449. [14] [14]DIMENY E M.Cardiovascular disease after renal transplantation[J].Kidney Int Suppl, 2002, (80) :78-84. [15] [15]BENNET A M, VAN MAARLE MC, HALLQVIST J, et al.Association of TNF-alpha serum levels and TNFA promoterpolymorphisms with risk of myocardial infarction[J].Atherosclerosis, 2005, 187 (2) :408-414. [16] [16]BODET C, CHANDAN F, GRENIER D.Porphyromonasgingivalis-induced inflammatory mediator profile in an exvivo human whole blood model[J].Clin Exp Immunol, 2005, 143 (1) :50-57. [17] [17]KURTIS B, TUTER G, SERDAR M, et al.Gingival crevicularfluid levels of monocyte chemoattractant protein-1and tumor necrosis factor-alpha in patients with chronicandaggressive periodontitis[J].J Periodontol, 2005, 76 (11) :1849-1855. [18] [18]HUJOEL P P, WHITE B A, GARCIAMI, et al.The dentogingival epithelial surface area revisited[J].J Periodontal Res, 2001, 36 (1) :48-55. [19] [19]ANNABLACH, EDWARD FRANEK, ARTUR WITULA.The influence of chronic periodontitison serum TNF-a, IL-6 and hs-CRPconcentrations, and function of graft andsurvival of kidney transplant recipients[J].Clin Transplant, 2009, 23 (2) :213-219. [20] [20]KEULERS B J, ROUMEN R H M, KEULERS M J, et al.Beeke IPHBilateral groin pain from a rotten molar[J].Lancet, 2005, 366 (9479) :94. [21] [21]LUND J P, DREWS T, HETZER R, er al.Oral surgicalmanagement of patients with mechanical circulatory support[J].Int J Oral Maxillofac Surg, 2003, 31 (6) :629-633. [22] [22]VELICH N, REMPORT A, SZABO G.Dental screening ofpatients after organ transplantation[J].Orv Hetil, 2002, 143 (10) :505-508. [23] [23]CENTERS FOR DISEASE CONTROL.Guidelines for preventing opportunistic infections among hematopoietic stem cell transplant recipients[J].MMWR Morb Mortal Wkly Rep, 2000, 49 (RR-10) :1-128. [24] [24]HURST P.Dental issues before and after organ transplantation[M].In:Stuart F P, Abecassis M M, Kaufman D B, editors.Organ transplantation.Georgetown (TX) :Landes Bioscience, 2000:517-522. [25] [25]GUGGENHEIM J, EGTHESAD B, STOCK D J.Dental management of the (solid) organ transplantpatient[J].Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 2003, 95 (4) 383-389. [26] [26]KIM E, GOLDMAN, DMD.Dental management of patients ith bone marrow and solid organ transplantation[J].Dent Clin N Am, 2006, 50 (4) :659-676. [27] [27]HOLT C D, WINSTON D J.Infections after liver transplantation[M].In:Busuttil R W, Klintmalm G K, eds.Transplantationof the Liver, 2nd ed.Philadelphia:Elsevier Saunder, 2005:963-994.
点击查看大图
计量
- 文章访问数: 2232
- HTML全文浏览量: 922
- PDF下载量: 83
- 被引次数: 0