Abstract: Objective To study the senile proximal humeral comminuted fracture, the method curative effect and indications of artificial humerus head replacement.Methods From March 2007 to August 2013, a total of 17 cases, according to Neer classified three or four parts of proximal humeral fracture and dislocation patients Ⅰperiod artificial humeral head replacement, aged 64-79, the average age of 70.2 years, surgical approach all USES the deltoid muscle pectoralis major clearance into the road, according to preoperative and intraoperative situation patients were given individualized rehabilitation plan line functional recovery.Results 17 cases were followed up for 8-29 months, an average of 14.7 months, there was no infection, no nerve injury, no dislocation, no prosthesis loosening, sinking, 1 case of heterotopic ossification, according to Neer criteria:6 cases were excellent, 8 cases were good, 3 cases fwere easible, the excellence and good rate was 82.3%.Conclusion The application of artificial humerus head replacement in the treatment of senile proximal humeral comminuted fracture has good curative effect, but preoperative assessment, intraoperative reconstruction of cuhk nodules and rotator cuff, postoperative rehabilitation training of individuation are important factors of functional recovery.