Q开关Nd:YAG治疗在色素性皮肤病中的疗效及对黑素代谢的影响

丁祖烈; 陈滔; 李盛华

Q开关Nd:YAG治疗在色素性皮肤病中的疗效及对黑素代谢的影响

攀枝花学院附属医院整形美容科

基金项目:

基金：国家自然科学基金资助项目 (81172832);

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出版历程
- 收稿日期: 2017-08-11

The Observation on the Effect of Q-Switching Nd:YAG Treatment in Pigmented Dermatoses and Influence for Melanin Metabolism

Funds:

基金：国家自然科学基金资助项目 (81172832);

摘要

摘要: 目的观察Q开关Nd:YAG治疗在色素性皮肤病中的疗效及对黑素代谢的影响程度.方法选取2015年10月至2016年8月期间攀枝花学院附属医院收治的114例色素性皮肤病患者为研究对象, 将114例患者随机分为对照组57例和观察组57例.对照组采用强脉冲光治疗, 观察组在对照组的基础上加用Q开关Nd:YAG治疗.比较2组患者临床总有效率、复发率、不良反应发生率、治疗前后的皮损评分、血清黑素代谢相关指标.结果观察组的临床总有效率高于对照组 (P<0.05) , 复发率低于对照组 (P<0.05) , 而2组的不良反应发生率比较, 差异无统计学意义 (P>0.05) , 治疗前2组患者的皮损评分及血清黑素代谢相关指标比较, 差异无统计学意义 (P>0.05) , 治疗后观察组的皮损评分及血清黑素代谢相关指标均好于对照组 (P<0.05) .结论 Q开关Nd:YAG治疗在色素性皮肤病中的临床疗效较好, 且对黑素代谢的影响更为积极, 因此在色素性皮肤病的治疗中具有较高的临床价值.
- Q开关Nd:YAG治疗 /
- 色素性皮肤病 /
- 临床疗效 /
- 黑素代谢 /
Abstract: Objective To observe the effect of Q-Switching Nd:YAG treatment in pigmented dermatoses and its influence for melanin metabolism. Methods 114 patients with pigmented dermatoses in our hospital from October 2015 to August 2016 were selected as the study object, and were randomly divided into the control group (57 cases) and the observation group (57 cases) .The control group were treated with intense pulsed light therapy while the observation group were treated with Q-Switching Nd:YAG treatment on the treatment of control group.Then the total effective rates, recurrence rates, adverse reaction rates, skin lesion scores and serum melanin metabolism related indexes before and after the treatment of two groups were analyzed and compared. Results Clinically, the total effective rates of observation group were higher than those of control group (P<0.05) and the recurrence rate of observation group was lower than that of control group (P<0.05) .The adverse reaction rates of two groups were compared and the differences were not statistically significant ( P >0.05) .The skin lesion scores and serum melanin metabolism related indexes of two groups before the treatment were compared and the differences were not statistically significant (P>0.05) .The serum melanin metabolism related indexes of two groups after the treatment were all better than those of control group ( P <0.05) . Conclusion The clinical effect of Q-Switching Nd:YAG treatment in the patients with pigmented dermatoses is better, and it has the active influence for the melanin metabolism, so it has higher clinical value in the treatment of pigmented dermatoses.
- Q-Switching Nd /
- YAG treatment /
- Pigmented dermatoses /
- Clinical effect /
- Melanin metabolism

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参考文献(17)

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