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基因沉默策略及其应用研究进展

周晓楠 宋雪兰 杨媛 马琛婧 何芳雁

周晓楠, 宋雪兰, 杨媛, 马琛婧, 何芳雁. 基因沉默策略及其应用研究进展[J]. 昆明医科大学学报, 2018, 39(01): 131-135.
引用本文: 周晓楠, 宋雪兰, 杨媛, 马琛婧, 何芳雁. 基因沉默策略及其应用研究进展[J]. 昆明医科大学学报, 2018, 39(01): 131-135.
Zhou Xiao Nan , Song Xue Lan , Yang Yuan , Ma Chen Jing , He Fang Yan . Advances and Applications in Gene Silencing[J]. Journal of Kunming Medical University, 2018, 39(01): 131-135.
Citation: Zhou Xiao Nan , Song Xue Lan , Yang Yuan , Ma Chen Jing , He Fang Yan . Advances and Applications in Gene Silencing[J]. Journal of Kunming Medical University, 2018, 39(01): 131-135.

基因沉默策略及其应用研究进展

基金项目: 

基金: 国家自然科学基金资助项目 (81560664, 81660677);

Advances and Applications in Gene Silencing

Funds: 

基金: 国家自然科学基金资助项目 (81560664, 81660677);

  • 摘要: 基因沉默 (Gene silencing) 是生物体中特定基因由于各种原因不表达或表达减少的现象, 是通过表观遗传控制基因表达的重要机制, 通过基因沉默技术探索疑难疾病的治疗方法是当下的研究热点.随着基因工程的迅速发展, 基因沉默技术不断有新技术出现取代已有的技术.对基因沉默技术所包括的核酶技术、反义寡核酸技术、基因敲除、RNA干扰技术及其应用进行介绍.
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  • 收稿日期:  2017-10-06

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