滇重楼散外敷联合抗结核药治疗浅表淋巴结结核的近期疗效
The Short-Term Effect of Paris Poiyphylla Smith var.Yunnanensis Powder Combined with Anti-tuberculosis Drugs in the Treatment of Superficial Lymph Node Tuberculosis
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摘要: 目的 观察滇重楼散外敷联合抗结核药治疗浅表淋巴结结核的近期疗效.方法 选择昆明市第三人民医院中西医收治的诊断为“浅表淋巴结结核”患者共170例, 随机分为对照组80例, 观察组90例, 观察组分为结节型、浸润型、脓肿型各30例.各组均内服HRZE (异烟肼、利福平、吡嗪酰胺、乙胺丁醇) 抗结核治疗.观察组加用冰片、细辛、白醋调滇重楼粉外敷淋巴结.观察2组的近期疗效, 按中医疗效判定标准判定疗效.结果观察组的好转率为64.44%, 对照组为30%, 观察组的好转率高于对照组, 差异具有统计学意义 (P<0.01) .观察组中脓肿型好转率为76.67%、浸润型好转率为73.33%、结节型好转率为43.33%;经组间两两比较, 浸润型的治疗好转率高于结节型, 差异有统计学意义 (P<0.05) ;脓肿型的好转率高于结节型, 差异有统计学意义 (P<0.05) ;脓肿型的好转率与浸润型比较差异无统计学意义 (P>0.5) .结论 滇重楼散外敷配合抗结核药治疗浅表淋巴结结核可显著提高近期疗效, 脓肿型、浸润型淋巴结结核疗效更为显著.Abstract: Objective To observe the short-term effect of Paris polyphylla Smith var. yunnanensis powder combined with anti-tuberculosis drugs in the observation of superficial lymph node tuberculosis. Methods A total of170 patients were randomly divided into two groups: 80 in the control group and 90 in the observation group. The observation group consisted of nodular type, infiltrating type and abscess type, each of which had 30 cases. The control group were treated with Isoniazid, Rifampicin, Pyrazinamide and Ethambutol. Besides the four medications, the observation group were treated with external application of Paris polyphylla Smith var. yunnanensis.Results The response rate was 30.00% in the control group and 64.44% in the observation group. The response rate in the observation group was higher than that in the control group, with a statistically significant difference (P<0.01) . In the observation group, the response rates of abscess, infiltration and nodule were 76.67%, 73.33% and 43.33%, respectively.By the comparative analysis, the response rate of infiltration was higher than that of nodule (P<0.05) , with a significant difference; the response rate of abscess was also higher than that of nodule (P<0.05) , with a significant difference. There was no significant difference between the response rates of abscess and infiltration (P>0.5) .Conclusions The external application of Paris polyphylla Smith var. yunnanensis powder combined with anti-tuberculosis drugs is curative in the observation of superficial lymph node tuberculosis, especially in the types ofinfiltrating and abscess.
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