高频振荡通气对烟雾吸入性肺损伤致急性呼吸窘迫综合征患者的临床疗效
Clinical Curative Effects of High Frequency Oscillatory Ventilation on Acute Respiratory Distress Syndrome Caused by Smoke Inhalation Injury in the Lungs
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摘要: 目的 探讨烟雾吸入性肺损伤导致急性呼吸窘迫综合征 (ARDS) 患者治疗中高频振荡通气方式的临床价值.方法 选取2010至2015年入院治疗的烟雾吸入性肺损伤引发ARDS患者50例, 随机平均分为2组, 分别选择常规机械通气与高频振荡通气治疗.结果 治疗后2组患者PaO2、PaCO2、PaO2/FiO2均改善 (P<0.05) , 研究组患者改善明显优于对照组 (P<0.05) ;研究组患者通气时间与住院时间相比对照组明显缩短 (P<0.05) ;2组患者30 d内死亡率以及并发症发生率差异无统计学意义 (P>0.05) .结论 高频振荡通气治疗能够有效改善烟雾吸入性肺损伤引发ARDS, 提高患者氧合指标, 在临床预后改善方面没有发现明显的优势.Abstract: Objective To study the curative effect of high frequency oscillatory ventilation on acute respiratory distress syndrome (ARDS) caused by smoke inhalation injury in the lungs. Me thods Fifty ARDS patients with lung injury caused by smoke inhalation were selected from 2010 to 2015. Patients were randomly divided into two groups, respectively choosing conventional mechanical ventilation or high frequency oscillatory ventilation.Re s ults PaO2, PaCO2, and PaO2/FiO2 were improved in both groups after the treatment (P < 0.05) . Patients in the treatment group improved significantly compared to those in the control group (P < 0.05) . The ventilation time and length of hospital stay reduced significantly in the treatment group (P < 0.05) . No significant difference was found in mortality and complication rates in both groups within 30 days (P > 0.05) . Conclus ion High frequency oscillatory ventilation can effectively alleviate symptoms of ARDS caused by smoke inhalation injury in the lungs by improving oxygenation index. No obvious improvement is found in prognosis.
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