高频振荡通气对烟雾吸入性肺损伤致急性呼吸窘迫综合征患者的临床疗效
Clinical Curative Effects of High Frequency Oscillatory Ventilation on Acute Respiratory Distress Syndrome Caused by Smoke Inhalation Injury in the Lungs
-
摘要: 目的 探讨烟雾吸入性肺损伤导致急性呼吸窘迫综合征 (ARDS) 患者治疗中高频振荡通气方式的临床价值.方法 选取2010至2015年入院治疗的烟雾吸入性肺损伤引发ARDS患者50例, 随机平均分为2组, 分别选择常规机械通气与高频振荡通气治疗.结果 治疗后2组患者PaO2、PaCO2、PaO2/FiO2均改善 (P<0.05) , 研究组患者改善明显优于对照组 (P<0.05) ;研究组患者通气时间与住院时间相比对照组明显缩短 (P<0.05) ;2组患者30 d内死亡率以及并发症发生率差异无统计学意义 (P>0.05) .结论 高频振荡通气治疗能够有效改善烟雾吸入性肺损伤引发ARDS, 提高患者氧合指标, 在临床预后改善方面没有发现明显的优势.Abstract: Objective To study the curative effect of high frequency oscillatory ventilation on acute respiratory distress syndrome (ARDS) caused by smoke inhalation injury in the lungs. Me thods Fifty ARDS patients with lung injury caused by smoke inhalation were selected from 2010 to 2015. Patients were randomly divided into two groups, respectively choosing conventional mechanical ventilation or high frequency oscillatory ventilation.Re s ults PaO2, PaCO2, and PaO2/FiO2 were improved in both groups after the treatment (P < 0.05) . Patients in the treatment group improved significantly compared to those in the control group (P < 0.05) . The ventilation time and length of hospital stay reduced significantly in the treatment group (P < 0.05) . No significant difference was found in mortality and complication rates in both groups within 30 days (P > 0.05) . Conclus ion High frequency oscillatory ventilation can effectively alleviate symptoms of ARDS caused by smoke inhalation injury in the lungs by improving oxygenation index. No obvious improvement is found in prognosis.
-
[1]刘伟, 金发光.烟雾吸入性急性肺损伤/急性呼吸窘迫综合征的研究进展[J].国际呼吸杂志, 2007, 27 (4) :307-310. [2]吴施曼, 樊毫军, 侯世科, 等.烟雾吸入性损伤的治疗研究进展[J].中国中西医结合急救杂志, 2013, 20 (5) :318-320. [3]乔莉, 马元, 张劲松, 等.急性呼吸窘迫综合征:柏林标准[J].中华急诊医学杂志, 2012, 21 (9) :952-957. [4]姜毅, 韩志海, 段蕴铀, 等.烟雾吸人性急性肺损伤/急性呼吸窘迫综合征与细胞应激[J].国际呼吸杂志, 2013, 33 (6) :470-475. [5] 叶江枫, 袁名辉, 杨归兰, 等.呼吸道吸入性损伤的综合治疗50例分析[J].医学信息, 2013, 26 (7) :528. [6]王亿胜, 李宏云, 冯永海, 等.小潮气量通气对急性肺损伤/急性呼吸窘迫综合征高风险患者疗效及预后的影响[J].郑州大学学报 (医学版) , 2014, 23 (3) :393-397. [7]陈林, 尚游, 姚尚龙, 等.机械通气所致肺损伤的分子生物学机制研究进展[J].中华危重病急救医学, 2014, 26 (2) :126-128. [8]陈少霖, 赖剑波, 李敏, 等.适应性支持通气在急性呼吸窘迫综合征中实施肺保护性通气策略的应用研究[J].中国实验诊断学, 2012, 16 (6) :1016-1018. [9]王海旭, 孙同文, 万有栋, 等.高频振荡通气治疗急性呼吸窘迫综合征的荟萃分析和试验序贯分析[J].中华危重病急救医学, 2015, 27 (7) :552-5577. [10]李晓峰, 尤伟艳, 程青虹, 等.两种不同通气方式治疗成人急性呼吸窘迫综合征的疗效比较[J].中国老年学杂志, 2012, 32 (19) :4323-4325. [11]徐前程, 刘小彬, 陈尚华, 等.高频振荡通气对成人急性呼吸窘迫综合征患者预后影响的荟萃分析[J].中国急救医学, 2013, 33 (12) :1088-1094. [12]杜微, 刘大为, 石岩, 等.高频振荡通气的机制及临床应用[J].中国危重病急救医学, 2010, 22 (7) :443-446. -
点击查看大图
计量
- 文章访问数: 1633
- HTML全文浏览量: 544
- PDF下载量: 30
- 被引次数: 0
下载:
