2013年至2015年昆明地区普通人群HCV感染状况分析
An Analysis of the Status of General Population with HCV Infection in Kunming Region from 2013 to 2015
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摘要: 目的 云南吸毒人群丙型肝炎病毒 (HCV) 感染率高, 对普通人群HCV感染的防控工作面临严峻挑战.旨在研究分析昆明地区HCV感染人群流行病学特征, 为昆明地区HCV感染制定防控措施和开展科学防控干预提供一定的参考信息.方法 采用回顾性方法对2013年至2015年来昆明医科大学第二附属医院接受血清HCV-Ig G抗体检测的受检者160 239例进行血清流行病学的统计学分析.结果 2013年至2015年昆明地区普通人群HCV感染率分别为1.11%、1.04%和0.91%;男性明显高于女性 (男性1.30%vs.女性0.91%, P<0.05) ;3160岁中老年人高于其它年龄.结论 男性和3160岁中老年人为2013年至2015年昆明地区HCV感染的高发人群, 这种流行病学特征可为昆明地区开展对HCV感染及其导致肝硬化、肝功能衰竭和肝细胞癌的防控工作, 制定科学的策略和干预措施提供一定的参考和依据.Abstract: Objective The aim of this study was to analyze the HCV seroprevalence in the general population visiting the Second Affiliated Hospital of Kunming Medical University. Me thods Between January 2013 and December 2015, a total of 160, 239 subjects were screened for the presence of anti-HCV antibodies in blood serum. Anti-HCV antibodies in serum samples were detected by enzyme-linked immunosorbent assay (ELISA) .The results of anti-HCV were analyzed in the features of year, sex and age. Re s ults The HCV seroprevalence in the general population from 2013 to 2015 was 1.11%, 1.04% and 0.91%, respectively, which was significantly higher in men than in women (1.30% vs. 0.91%, P < 0.05) . The highest HCV seroprevalence occurred in aged31-65 years. Conclus ions The analysis of the data suggests that the features of HCV-positive including year, sex and age could be beneficial for formulating scientific strategy and intervention measures of HCV infection and liver cirrhosis, liver failure and hepatocellular carcinoma caused by HCV in Kunming.
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Key words:
- Hepatitis C Virus /
- Hepatitis C Virus Antibody /
- General Population /
- Infection rate /
- Seroepidemiology
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[1] [1]WHO.Viral hepatitis Sixty-third world health assembly provisional agenda item 11.12[R].Genera:WHO.2012. [2]刘建, 陈方方, 韩娟, 等.河南省驻马店市HIV感染者及艾滋病患者死亡原因分析[J].中华预防医学杂志, 2012, 46 (11) :1047-1049. [3] [3]ZHOU YH, LIU FL, YAO ZH, et al.Comparison of HIV-, HBV-, HCV-and co-infection prevalence between Chinese and Burmese intravenous drug users of the China-Myanmar border region[J].PLo S One, 2011, 6 (1) :e16349. [4]徐艳声, 梁军, 李平, 等.昆明市吸毒人员HCV感染及相关因素分析[J].皮肤病与性病, 2012, 34 (01) :49-51. [5] [5]CORNBERG M, RAZAVI H A, ALBERTI A, et al.A systematic review of hepatitis C virus epidemiology in Europe, Canada and Israel[J].Liver Int, 2011, 31 (2) :30-60. [6]包叶江, 陈卫平, 方任华, 等.2004-2012年丙型肝炎的流行特征分析[J].中华医院感染学杂志, 2015, 25 (19) :4469-4477. [7] 陈园生, 李黎, 崔富强, 等.中国丙型肝炎血清流行病学研究[J].中华流行病学杂志, 2011, 32 (9) :888-891. [8]何丽, 林栋羚, 姚玉红, 等.新疆乌鲁木齐地区某农牧区丙型肝炎病毒血清流行病学研究[J].新疆医科大学学报, 2017, 40 (08) :1088-1092. [9]李彤, 沈云松.云南省昆明市正常人群HCV感染的流行病学调查[J].中国现代医生, 2016, 54 (07) :127-130. [10]李程, 朱琳, 邢俊, 等.大连市2014年丙型病毒性肝炎疫情分析[J/OL].上海预防医学, 2016, 28 (08) :537-538. [11]姜春红, 苏秋菊, 赵文彬.2010年至2014年鞍山市丙型病毒性肝炎流行病学特征分析[J].中国现代医生, 2015, 53 (30) :124-130. [12] [12]KHAYRIYYAH M H, JUSTINA G, FLAXMAN A D, et al.Global epidemiology of hepatitis C virus infection:New estimates of age-specific antibody to HCV seroprevalence[J].Hepatology, 2013, 57 (4) :1333-1342. -

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