Abstract: Objective To investigate whether the transcatheter closure of funnel shaped patent ductus arteriosus (PDA) under the guidance of transthoracic ultrasound can be used as a modified treatment method for traditional PDA closure, so as to shorten the time for operation, patients and operators under the X-ray, and to generalize the method. Methods There were 115 FDA cases of 1-14 year-old with an average in 3.5, who were chosen from September 2015 to September 2017 of the First Affiliated Hospital of Kunming Medical University, which were excluded from cardiovascular malformations and divided into observation group by 66 cases in random, and the rest 49 cases were selected as control group. Traditional descending aortographies and the X-ray guiding were applied to the control group. Results The accuracy of the experimental group was higher than that of the control group when the narrowest arterial duct rages from 2 mm to 8 mm, the differences was statically significant (P <0.05) . Also, the incidence of operative complications was statistically significant (P < 0.05) . Conclusion TTE guided PDA closure has the advantages of simple operating, time saving, without contrast media using, safety and reliability, wide operation and low cost, it has great potential for development and broad application.