Clinical Epidemiology Investigation of Inpatients with Urolithiasis
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摘要:
目的 回顾性研究尿石症患者临床资料,为区域性泌尿结石防治提供临床依据。 方法 抽取2016、2017年昆明医科大学第二附属医院泌尿外科尿石症患者的病历资料,进行回顾性调查。 结果 调查的6 545例尿石症患者占同期泌尿外科住院患者的47.8%,男∶女 = 2.12∶1,高发年龄介于41~60岁,占67.8%。职业构成比以农民为主体(33.9%)。超重与肥胖的患者占比分别为30.5%、18.5%。泌尿系结石以上尿路结石多见,不同性别结石部位分布存在差异(P < 0.05)。463份结石成分中,草酸钙结石成分占68%,混合结石占79%;结石CT值平均数为(837.2±286.1)HU,小于500 HU以尿酸结石成分多见(75.7%),大于800 HU以含钙结石成分多见(67.2%),500~800 HU之间以感染类结石(磷酸铵镁/磷酸磷灰石)成分多见(85%);463 位患者尿pH值 < 5时尿酸结石成分占72.7%;pH > 6.5时感染类结石成分占92%;5≤pH≤6.5时含钙结石成分占67.1%。 结论 (1)尿石症患者占同期泌尿外科住院患者比率较高,提示尿石症是云南省最常见的泌尿外科疾病;男性多于女性,41~60岁高发;职业构成比以农民为主体。(2)尿石症以上尿路结石多见,不同性别结石部位分布存在差异。(3)不同结石成分CT值存在差异,尿酸结石CT值 < 500 HU;感染类结石CT值介于500 HU到800 HU之间;含钙结石CT值多 > 800 HU。(4)尿pH值是影响结石形成的重要因,酸性尿中容易形成尿酸结石,碱性尿中易形成感染类结石。 Abstract:Objective To provide clinical basis for the prevention and treatment of regional urinary calculi by retrospectively analyzing the clinical data of urolithiasis patients. Methods The medical records of patients with urinary calculi in 2016 and 2017 in the Department of Urology, Second Affiliated Hospital of Kunming Medical University were collected and retrospectively investigated. Results There were 6545 urolithiasis patients in 2016 and 2017, which accounted for 47.8% of hospitalized patients in urology department with the same period, with the ration of 2.12∶1 between male and female patients. In this group, the high-incidence age was between 41 and 60 years old (67.8%), and the farmers (33.9%) were the main occupation. Also, we found the in-patients of overweight and obesity was 30.5% and 18.5% respectively. Statistically, the upper urinary calculi were most common in urinary calculi, and the distribution of calculi was different in different genders(P < 0.05). The 463 reports our researchers investigated showed that the calcium oxalate stone composition accounted for the highest proportion, up to 68% and mixed component stones occupied 79%. The average CT value of calculi was 837.2±286.1 HU. 75.7% calculi with CT value less than 500 HU were uric acid stones, 67.2% calculi with CT value more than 800 HU were calcium stone, and 85% calculi with CT value between 500~800 HU were infectious calculi (magnesium ammonium phosphate/phosphorite apatite). The urinary PH of calculi patients was 6.3 ± 0.9. The main component of calculi in patients with urine pH < 5 was uric acid, accounting for 72.7%; the main component of calculi in patients with urine pH > 6.5 was infected calculi, accounting for 92%; the main component of calculi in patients with urine 5≤pH≤6.5 was calcium stone, accounting for 67.1%. Conclusions (1) This group of urolithiasis patients accounted for a higher proportion of urological inpatients in the same period, suggesting that urolithiasis is the most common urological disease in Yunnan Province; There are more men than women in urolithiasis, the high incidence age is 41-60 years old; The farmers are the main occupation. (2) Upper urinary calculi are more common in urolithiasis, and the distribution of calculi was different in different genders. (3) The CT values of stones with different components are different. The CT value of uric acid stones is below 500 HU; the CT value of infected stones ranges from 500 HU to 800 HU; the CT value of calcium-containing stones is above 800 HU. (4) Urine pH is an important factor affecting the formation of calculi. Acidic urine is easy to form uric acid stones, and alkaline urine are easy to form infected stones . -
Key words:
- Urolithiasis /
- Inpatients /
- Clinical epidemiology
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表 1 不同性别尿石患者结石部位分布[n(%)]
Table 1. Distribution of stone sites in urolithiasis patients [n(%)]
性别 上尿路 下尿路 上下尿路 χ2 P 男性 4214(94.8) 116(2.6) 116(2.6) 57.800 < 0.001 女性 2071(98.7) 9(0.4) 19(0.9) -
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