肺部微生态与肺癌的相关性研究进展

宁明杰; 陈颖

doi:10.12259/j.issn.2095-610X.S20210336

肺部微生态与肺癌的相关性研究进展

doi: 10.12259/j.issn.2095-610X.S20210336

宁明杰,
陈颖^,

昆明医科大学第三附属医院胸外一科，云南省肿瘤医院，云南省癌症中心，高海拔地区肿瘤国际合作重点实验室，云南昆明　650118

基金项目: 国家自然科学基金资助项目（81702274），云南省科技厅-昆明医科大学应用基础研究联合专项基金资助项目（2017FE468-159），云南省卫健委医学科学带头人培养计划资助项目（H-2018025）

详细信息

作者简介:
宁明杰（1995～），女，吉林榆树人，在读硕士研究生，主要从事胸外科临床工作

通讯作者:
陈颖，E-mail： 36410008@qq.com

中图分类号: R743.2
计量
- 文章访问数: 3425
- HTML全文浏览量: 2374
- PDF下载量: 40
- 被引次数: 0
出版历程
- 收稿日期: 2020-12-16
- 刊出日期: 2021-03-25

Research Progress of The Correlation between Lung Microbiome and Lung Cancer

Ming-jie NING,
Ying CHEN^,

Dept. of Thoracic Surgery Ι，The Third Affiliated Hospital of Kunming Medical University，Yunnan Cancer Hospital，Yunnan Cancer Center，The International Cooperation Key Laboratory of Regional Tumor in High Altitude Area，Kunming Yunnan 650118，China

摘要

摘要: 近年来肺部微生态开始成为微生物组学研究的热点。健康人群和肺癌患者在肺部微生物群落存在差异，环境因素、吸烟、遗传对肺部微生态及肺癌的发生发展有关联。有研究发现肺癌患者的下呼吸道微生物的组成与健康人群显著不同。所以通过改善肺部微生态，抑制肺癌的发生发展的微环境，可能为肺癌早期防治和个性化治疗提供新策略。就肺部微生态的与肺癌相关研究进展作一综述。
- 肺部微生态 /
- 肺癌 /
- 生态失调 /
- 致癌作用
Abstract: Lung microbiome has become a hot topic in microbiome research field in recent years. Lung mircrobiota is different between healthy people and lung cancer patients. Environmental factors, smoking, genetic affect the lung microbiome and the development of lung cancer. Studies have found that the composition of the lower respiratory tract microorganisms of lung cancer patients is significantly different from that of healthy people. Therefore, improving lung microbiome to inhibit lung cancer, may promote the development of innovative strategies for early prevention and personalized treatment in lung cancer. This article reviewed the research on the corrrelation between lung microbiome between lung cancer.
- Lung microbiome /
- Lung cancer /
- Dysbiosis /
- Carcinogenesis

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参考文献(49)

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