Advantages of 3D-DSA in Neurointervention
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摘要:
目的 浅析“金标准”内3D-DSA技术较常规2D-DSA在神经介入中的诊断优势和治疗中的应用价值。 方法 收集昆明医科大学附属延安医院2018年1月至2019年12月使用2D及3D-DSA技术行神经介入患者277例。其中:脑血栓取栓111例、动脉瘤106例137个(普通囊状动脉瘤75例97个、巨大型动脉瘤5例6个、宽颈动脉瘤21例29个、夹层动脉瘤等2例2个、梭形动脉瘤2例2个、复杂型动脉瘤1例1个)、动静脉畸形45例、颈动脉狭窄支架置入15例。由工作经验丰富的2位副高以上阅片者采用双盲法对2D和3D的图像进行回顾性分析与测量,进而比较2D、3D图像测量数据差异及疾病检出率。 结果 2D-DSA在普通脑血栓对各段血管的显示率与3D-DSA,差异无统计学意义(P > 0.05);2D-DSA检出动脉瘤93例(122个),3D-DSA检出106例(137个)( P < 0.05),不含假阳性2例;2D-DSA检出动静脉畸形44例,3D-DSA检出45例( P > 0.05);2D-DSA显示颈动脉狭窄15例,3D-DSA检出15例,差异无统计学意义( P > 0.05)。3D-DSA在颅内动脉瘤检出率、瘤颈、瘤体形态、瘤径、载瘤血管、穿支血管显示等方面显示效果明显优于2D-DSA。 结论 3D-DSA技术提高了对神经性疾病的检出率;同时也提高了对疾病的定性、定量诊断准确率;并且对疾病的进一步治疗有重要的指导意义。 Abstract:Objective To analyse the diagnostic advantages and therapeutic value of 3D-DSA compared with conventional 2D-DSA in nerointervention in the “Gold Standard”. Methods A total of 277 cases who underwent neurointerventional therapy using 2D and 3D-DSA were collected from the Affiliated Yan’ an Hospital of Kunming Medical University from January 2018 to December 2019, including 111 cases of cerebral thrombectomy, 106 cases/137 aneurysms (97 common cystic aneurysms in 75 cases, 6 giant aneurysms in 5 cases, 29 wide neck aneurysms in 21 cases, 2 dissecting aneurysms in 2 cases, 2 spindle aneurysms in 2 cases, 1 complex aneurysm in 1 case), 45 cases of arteriovenous malformation and 15 cases of carotid artery stenosis stent implantation. The 2D and 3D images were retrospectively analyzed and measured by two experienced radiologists using double-blind method, and then the difference of the measured data and the detection rate of the disease were compared. Results There was no significant difference between 2D-DSA and 3D-DSA in the detection rate of each segment of cerebral thrombosis (P > 0.05). 122 aneurysms (93 cases) were detected by 2D-DSA, 137 aneurysms (106 cases) were detected by 3D-DSA ( P < 0.05), excepted 2 false positive cases. 44 cases of AVM were detected by 2D-DSA and 45 cases were detected by 3D-DSA ( P > 0.05). 2D-DSA showed carotid artery stenosis in 15 cases and 3D-DSA showed carotid artery stenosis in 15 cases, the difference was not statistically significant ( P > 0.05). 3D-DSA is significantly better than 2D-DSA in the detection rate of intracranial aneurysm, tumor neck, tumor shape, tumor diameter, tumor tumor-bearing vessels, perforator vessel, etc. Conclusion 3D-DSA technology improves the detection rate of neurological diseases, improves the accuracy of qualitative and quantitative diagnosis of neurological diseases; therefore it has important guiding significance for the further treatment of diseases. -
Key words:
- 3D-DSA /
- Neurointervention /
- Cerebral angiography
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表 1 2D-DSA、3D-DSA在脑血栓取栓后远端血管显示及分支显示统计[n(%)]
Table 1. Comparison of 2D-DSA and 3D-DSA in displaying distal vessels and branches after thrombectomy [n(%)]
项目 2D-DSA 3D-DSA P − 15(13.9) 15(13.5) 1.000 + 15(13.9) 19(17.1) 0.835 ++ 78(72.2) 77(69.4) 0.731 总计 108 111 0.679 表 2 2D-DSA、3D-DSA在脑动脉瘤颈与载瘤动脉关系统计[n(%)]
Table 2. Comparison of 2D-DSA and 3D-DSA in aneurysm neck and parent artery [n(%)]
项目 2D-DSA 3D-DSA P 普通囊状动脉瘤 71(51.8) 97(70.8) 0.012* 巨大型动脉瘤 2(1.5) 2(1.5) 1.000 宽颈动脉瘤 25(18.2) 29(21.2) 0.042* 夹层动脉瘤 2(1.5) 2(1.5) 1.000 梭形动脉瘤 2(1.5) 2(1.5) 1.000 复杂型动脉瘤 1(0.7) 1(0.7) 1.000 总计 122 137 0.009* *P < 0.05。 表 3 不同形态动脉瘤显示统计[n(%)]
Table 3. Comparison of different shapes of aneurysms [n(%)]
项目 2D-DSA 3D-DSA P − 5(16.1) 0 − + 5(16.1) 3(9.6) < 0.001* ++ 14(45.1) 27(87.1) < 0.001* 总计 24(77.4) 31(100) 0.019* *P < 0.05。 -
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