Effect of Intermittent Prone Position on Neonatal Respiratory Distress Syndrome
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摘要:
目的 探究间歇俯卧位通气在新生儿呼吸窘迫综合征(NRDS)中的应用效果。 方法 将云南省第三人民医院儿科新生儿监护室2020年1月至2020年12月进行机械通气的NRDS患儿120例,按照数字表法随机分为实验组、对照组各60例,实验组患儿给予间歇俯卧位,即俯卧2 h-左侧卧位1 h-俯卧位2 h-右侧卧位1 h交替更换患儿体位,每日持续应用俯卧位16 h,对照组采取常规仰卧位护理,收集并分析实验组与对照组患儿治疗前、治疗后2 h、24 h的血气分析指标、住院天数及呼吸机辅助通气时长。 结果 2组患儿在治疗后2 h的经皮血氧饱和度(SpO2)、治疗后24 h的动脉氧分压(PaO2)、动脉二氧化碳分压(PaCO2)及氧合指数(PaO2/FiO2)差异有统计学意义(P < 0.05);在治疗后2 h的PaO2、PaCO2、PaO2/FiO2及治疗后24 h的SpO2差异无统计学意义(P > 0.05)。实验组患儿在呼吸机治疗时间、住院天数上显著低于对照组,差异有统计学意义(P < 0.05)。 结论 间歇俯卧位能够有效改善呼吸窘迫新生儿的通气/换气功能,缓解其呼吸窘迫症状,缩短患儿的呼吸机辅助通气时间。 -
关键词:
- 俯卧位 /
- 新生儿呼吸窘迫综合征 /
- 应用效果
Abstract:Objective To investigate the effect of intermittent prone position ventilation in neonatal respiratory distress syndrome (NRDS) in rats. Methods 120 cases of NRDS children undergoing mechanical ventilation from January 2020 to December 2020 in the pediatric neonatal intensive care unit of the Third People’ s Hospital of Yunnan Province, It was divided into experimental group and control group, 60 cases each, The experimental group was given intermittent prone position, that is, prone 2 h-left position 1 h- prone position 2 h-right position 1 h alternately change the position of the child, apply for 16 hours per day, of prone position daily The control group took routine supine nursing, collect and analyze blood and gas analysis indexes, hospitalization days, Mechanical ventilation duration between experimental and control children. Results Percutaneous oxygen saturation (SpO2), arterial oxygen partial pressure (PaO2), arterial carbon dioxide partial pressure (PaCO2) and oxygenation index (PaO2/FiO2) were significantly different between the two groups after treatment (P < 0.05); There was no significant difference in the PaO2、PaCO2、PaO2/FiO2 of 2 h after treatment and the SpO2 of 24 h after treatment (P > 0.05). The experimental group was significantly lower than the control group in ventilator treatment time and hospitalization days, difference was statistically significant (P < 0.05). Conclusion Intermittent prone position can effectively improve the ventilation / ventilation function of newborns with respiratory distress, relieve their respiratory distress symptoms, and shorten the ventilator-assisted ventilation time of children. -
表 1 两组患儿性别、出生体质量、胎龄比较结果 [
$\bar x \pm s$ /n(%)]Table 1. Comparison of gender,birth weight and gestational between two groups [
$\bar x \pm s$ /n(%)]临床资料 实验组(n = 60) 对照组(n = 60) χ2/t P 男 39(65.00) 41(68.33) 0.037 0.847 出生体重(g) 2165.17 ± 498.56 2108.17 ± 429.21 0.671 0.503 胎龄(周) 36.77 ± 1.56 36.97 ± 1.60 0.685 0.495 表 2 两组患儿血气、氧合指数比较结果(
$\bar x \pm s$ )(1)Table 2. Comparison of blood gas and oxygenation index between two groups (
$\bar x \pm s$ )(1)组别 SpO2(%) PaO2(mmHg) 治疗前 治疗后2 h 治疗后24 h 治疗前 治疗后2 h 治疗后24 h 实验组(n = 60) 74.70 ± 5.76 88.93 ± 2.77* 93.75 ± 1.58 57.16 ± 14.47 58.85 ± 11.56 73.94 ± 8.01* 对照组(n = 60) 74.59 ± 5.67 82.68 ± 2.62 93.63 ± 1.77 56.88 ± 13.13 57.87 ± 10.76 68.60 ± 11.64 t 0.112 12.690 0.380 0.471 0.481 2.929 p 0.911 0.000 0.704 0.913 0.631 0.004 表2 两组患儿血气、氧合指数比较结果($\bar x \pm s$)(2) Tab.2 Comparison of blood gas and oxygenation index between two groups ($\bar x \pm s$)(2) 组别 PaCO2(mmHg) PaO2/FiO2(mmHg) 治疗前 治疗后2 h 治疗后24 h 治疗前 治疗后2 h 治疗后24 h 实验组(n = 60) 48.55 ± 13.90 46.68 ± 11.10 40.34 ± 6.22* 171.12 ± 48.38 177.66 ± 47.79 227.11 ± 32.99* 对照组(n = 60) 48.29 ± 13.19 47.78 ± 9.82 45.65 ± 8.92 170.65 ± 46.27 173.37 ± 39.21 187.15 ± 45.54 t 0.565 −0.571 −3.779 0.054 0.537 5.504 P 0.913 0.569 0.000 0.957 0.592 0.000 与对照组比较,*P < 0.05。 表 3 两组患儿住院天数、呼吸机治疗时间比较结果(
$\bar x \pm s$ )Table 3. Comparison of hospitalization days and ventilator treatment time between two groups (
$\bar x \pm s$ )组别 平均住院天数(d) 呼吸机治疗时间(d) 实验组(n = 60) 12.77 ± 3.77* 4.18 ± 1.67* 对照组(n = 60) 16.73 ± 5.85 6.63 ± 1.62 t 4.144 8.163 P < 0.001 < 0.001 与对照组比较,*P < 0.05。 -
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