Effect of Standard Nutrition Intervention on Quality of Life in Patients with Rhinitis after Radiotherapy
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摘要:
目的 探讨规范化营养管理对鼻咽癌放疗患者生活质量的影响。 方法 选取某三级甲等肿瘤医院接受放射治疗的鼻咽癌患者160例作为研究对象，随机分为对照组和观察组，每组80例，对照组行常规护理，观察组在常规护理基础上，行规范化营养管理。对比两组患者营养学指标Hb、PA、ALB及生存质量（FACT-H&N量表）。 结果 规范化营养管理的观察组各营养指标值均高于对照组，差异有统计学意义（P < 0.05）；2组患者使用FACT-H&N量表进行评估，观察组总分值均高于对照组，差异有统计学意义（P < 0.05）。 结论 鼻咽癌患者放疗期间行规范化营养管理能有效维持患者的正常营养指标，提高生活质量。 Abstract:Objective To explore the effect of standardized nutrition management on the quality of life of patients with nasopharyngeal carcinoma after radiotherapy. Methods 160 patients with nasopharyngeal carcinoma who received radiotherapy in a 3A tumor hospital were randomly divided into control group and observation group, 80 cases in each group. The control group received routine nursing, while the observation group received standardized nutrition management on the basis of routine nursing. Hb, PA, ALB and quality of life were compared between the two groups （FACT-H & N Scale）. Results The nutritional index of the observation group was higher than that of the control group after standardized nutrition management, and the study was statistically significant （P < 0.05）; The total score of the patients in the observation group was higher than that of the control group （P < 0.05）. Conclusion Standardized nutrition management can effectively maintain the normal nutritional indicators and improve the quality of life of patients with nasopharyngeal carcinoma during radiotherapy. -
表 1 2组患者营养相关的血液指标比较（
$ \bar x \pm s $ ）Table 1. Comparison of nutritional related blood indexes between the two groups （
$\bar x \pm s $ ）项目 放疗前 放疗4周 放疗结束 F P Hb（g/L） 对照组 131.84 ± 12.04 123.76 ± 11.25 106.74 ± 9.85 F1 = 60.76 0.000* 观察组 132.65 ± 11.16 131.17 ± 10.77 130.54 ± 10.87 F2 = 9.071 0.002* t −1.601 −2.443 −4.156 F3 = 7.007 0.004* P 0.125 0.015 0.000 PA（mg/L） 对照组 270.64 ± 21.19 234.94 ± 16.43 210.05 ± 14.57 F1 = 58.65 0.000* 观察组 271.17 ± 23.43 268.06 ± 22.31 267.25 ± 19.76 F2 = 4.014 0.049* t −0.084 −2.443 −2.287 F3 = 4.052 0.025* P 0.854 0.031 0.028 ALB（g/L） 对照组 43.74 ± 4.21 37.81 ± 4.33 34.86 ± 1.75 F1 = 7.658 0.001* 观察组 44.05 ± 3.91 42.75 ± 4.12 41.18 ± 3.77 F2 = 0.003 0.961 t 0.785 −0.458 −1.361 F3 = 0.476 0.570 P 0.602 0.712 0.173 注：F1是时间效应；F2是分组效应；F3是时间与分组交互作用。*P < 0.05。 
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表 2 2组患者放疗前后FACT-H&N评分比较[（
$ \bar x \pm s $ ），分]Table 2. Comparison of FACT-H & N scores between the two groups before and after radiotherapy [（
$ \bar x \pm s $ ），points]组别 放疗前 放疗后 P 观察组
（n = 80）106.28 ± 5.63 91.39 ± 7.54 < 0.05 对照组
（n = 80）105.19 ± 5.74 79.85 ± 5.53 < 0.05 t 11.35 6.32 P 1.234 < 0.05
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