Effect of Moist Exposed Burn Ointment on Retention Time of Positive Pressure Venous Needle in Neurosurgery Department
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摘要:
目的 观察湿热烧伤膏对经正压静脉留置针输注特殊药物患者的正压静脉留置针留置时间的影响。 方法 选取昆明医科大学第三附属医院神经外科200例经正压静脉留置针输注高浓度、高刺激性药物患者,随机分为观察组及对照组(每组各100例),观察组应用湿热烧伤膏沿静脉走向涂抹厚度约1~2 mm,外层包裹保鲜膜,每日用药2次;对照组不使用任何药物干预,只采取常规护理措施。比较并发症发生率、留置针留置时间。 结果 正压静脉留置针置时间达72 h者,观察组为95%,对照组为76%,2组比较,差异有统计学意义(P < 0.05);2组并发症发生率比较,观察组为4%,对照组34%,差异有统计学意义(P < 0.05);2组满意度比较,对照组为96%,观察组78%,差异有统计学意义(P < 0.05)。 结论 湿润烧伤膏对肿瘤神经外科经正压静脉留置针输注高浓度、高刺激性的特殊药物患者延长留置针留置时间、减少并发症效果显著,且经济实惠,值得临床借鉴。 Abstract:Objective To investigate the effect of Moist Exposed Burn Ointment on the retaining time of positive-pressure intravenous indwelling needle in patients with infusion of special medications. Methods A total of 200 patients in our department who received high-concentration and highly irritating drugs via positive pressure intravenous indwelling needles were randomly divided into experimental group and control group (100 cases in each group). In experimental group, the Moist Exposed Burn Ointment was applied with a thickness of about 1~2 mm along the vein and wrapped with plastic wrap, twice a day. In control group routine nursing measures were used without any other drug intervention. The incidence of complications and the retaining time of indwelling needle were compared. Results 95% of the patients in the experimental group had an needle retention time of 72 h, while in the control group, only 76% of the patients had retention time of 72 h, and the difference was statistically significant (P < 0.05). The incidence of complications was 4% in the experimental group and 34% in the control group, with statistically significant difference between the two groups (P < 0.05). The satisfaction rate of the two groups was 96% in the control group and 78% in the observation group, and the difference was statistically significant (P < 0.05). Conclusion MEBO is effective in prolonging the retention time of the indwelling needle and reducing complications for patients with high-concentration and highly irritating drugs infused with a positive pressure intravenous indwelling needle in tumor neurosurgery. It is economical and worthy of clinical application. -
表 1 2组患者正压静脉留置针留置时间的比例[n(%)]
Table 1. The proportion of the positive pressure venous indwelling needle indwelling in the two groups [n(%)]
组别 n 留置时间 = 72 h 留置时间 < 72 h χ2 P 对照组 100 76(76.0) 24(24.0) 14.559 0.000* 观察组 100 95(95.0) 5(5.0) *P < 0.05。 表 2 2组患者对正压静脉留置针输液的满意情况比例[n(%)]
Table 2. The proportion of patients in the two groups who are satisfied with the positive pressure intravenous indwelling needle infusion [n(%)]
组别 n 非常满意 基本满意 不满意 满意率 χ2 P 对照组 100 50(50.0) 28(28.0) 22(22.0) 78(78.0) 14.252 0.000* 观察组 100 78(78.0) 18(18.0) 4(4.0) 96(96.0) *P < 0.05。 表 3 2组患者并发症发生情况比例[n(%)]
Table 3. Proportion of complications in the two groups of patients [n(%)]
组别 n 液体渗漏 静脉炎 皮肤肿胀 血栓形成 并发症发生率 对照组 100 11(11.0) 6(6.0) 15(15.0) 2(2.0) 34(34.0) 观察组 100 1(1.0) 1(1.0) 2(2.0) 0(0.0) 4(4.0) χ2 29.094 P 0.000* *P < 0.05。 -
[1] 蒋琳,徐新新,杨宇莹,等. 生理盐水与肠外营养液同时匀速输注预防静脉炎的临床效果观察[J]. 新疆医科大学学报,2015,38(9):1159-1161. doi: 10.3969/j.issn.1009-5551.2015.09.024 [2] 中华人民共和国国家卫生和计划生育委员会. WS/T433-2013静脉治疗护理操作技术规范[S]. 中国质检出版社, WST4332013.2013. [3] 贺书霞. 静脉输液外渗的原因分析及其预防护理[J]. 中国实用医药,2016,11(22):208-209. [4] 邱家英,左焕,袁碧芳,等. 季德胜蛇酒酒精混合物治疗脂肪乳静脉注射输液外渗的效果观察[J]. 四川医学,2016,36(2):228-229. [5] Wei W,Liu Q J,Tan Y,et al. Oxidative Stress,diabetes,and Diabetic Complications[J]. Hemoglobin,2009,33(5):370-377. doi: 10.3109/03630260903212175 [6] Tang Q L,Han S S,Feng J,et al. Moist exposed burn ointment promotes cutaneous excisional wound healing in rats involving VEGF and bFGF[J]. Mol Med Rep,2014,9(4):1277-1282. doi: 10.3892/mmr.2014.1921 [7] 杨新蕾,许建允,孟红阳. 湿润烧伤膏治疗供皮区残余创面的疗效观察[J]. 当代医学,2021,27(12):121-122. doi: 10.3969/j.issn.1009-4393.2021.12.048 [8] 乾利,黄欣,王宇,等. 湿润暴露疗法/湿润烧伤膏治疗慢性难愈合创面的超微病理及丝裂原活化蛋白激酶激酶和c-myc mRNA 表达的机制研究[J]. 中国全科医学,2015,18(3):294-299. doi: 10.3969/j.issn.1007-9572.2015.03.17 [9] 张静,刘春,刘小丽,等. 美宝湿润烧伤膏联合硫酸镁用于静脉输入蔗糖铁外渗患者的护理体会[J]. 中国社区医师,2020,36(1):136-138. doi: 10.3969/j.issn.1007-614x.2020.01.082 [10] 蒋子文,王慧娟. 湿润烧伤膏联合重组人表皮生长因子对混合痔术后伤口愈合的影响[J]. 基层医学论坛,2020,24(1):53-54. [11] 朱登玲,王霞,姜阿利,等. 原位再生技术治疗71例糖尿病足疗效观察[J]. 中国烧伤疮疡杂志,2017,29(3):186-190. [12] 张丽艳,袁继龙. 湿润烧伤膏治疗难愈性创面的临床疗效观察[J]. 辽宁医学杂志,2019,33(2):53-55. [13] Li H L,Deng Y T,Zhang Z R,et al. Evaluation of effectiveness in a novel wound healing ointment-crocodile oil burn ointment[J]. Afr J Tradit Complement Alterm Med,2016,14(1):62-72. doi: 10.21010/ajtcam.v14i1.8 [14] 王澍,葛斌,唐乾利,等. MEBT/MEBO对慢性难愈合创面组织中EGFR表达的影响[J]. 中国烧伤疮疡杂志,2018,30(1):1-11. [15] 晏爱珍,底大可,曾小芳,等. 美宝湿润烧伤膏油纱在寻常型天疱疮创面护理中的效果[J]. 广东医学,2017,38(16):2580-2581. doi: 10.3969/j.issn.1001-9448.2017.16.047 [16] 张续兰,张红,高欣,等. 湿润烧伤膏在放疗患者皮肤损伤中的临床运用[J]. 甘肃医药,2015,34(4):284-286. [17] 李杰辉,黄欣,唐乾利,等. MEBT/MEBO治疗糖尿病足溃疡的临床疗效观察[J]. 中国烧伤疮疡杂志,2016,28(1):22-25. [18] 刘井双,于艳梅,高志辉,等. 原位再生医疗技术治疗糖尿病足疗效观察[J]. 中国烧伤疮疡杂志,2017,29(4):262-266. [19] 朱坤锁. 美宝湿润烧伤膏在激光祛斑创面治疗中的临床效果[J]. 皮肤病与性病杂志,2019,4(2):300-301. [20] 毕所峰. 湿润烧伤膏治疗深度烧伤后期残余创面67例临床观察[J]. 中国农村卫生,2017,9(19):53-54.